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Pharmaceutical industry news

Fresh coverage across pharma, biotech, medtech, research, approvals, and market-moving developments.

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NIH award: Regulation of Gut Lipid Metabolism and Sexually Dimorphic Longevity by Hypothalamic-Like Neurons in C. elegans

Recipient: COLUMBIA UNIV NEW YORK MORNINGSIDE. Award amount: 132300.

NIH RePORTEROriginal source
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NIH award: Mitigating the renal consequences of extreme heat in older adults

Recipient: UNIVERSITY OF ARKANSAS AT FAYETTEVILLE. Award amount: 119448.

NIH RePORTEROriginal source
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NIH award: Aligning Hospital Admission Decisions with Health Priorities of People with Alzheimer's Disease and Related Dementias

Recipient: BAYLOR COLLEGE OF MEDICINE. Award amount: 161883.

NIH RePORTEROriginal source
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NIH award: A Pragmatic Randomized Controlled Trial of Brief Meaning Centered Psychotherapy for Patients with Advanced Cancer Receiving Homecare

Recipient: SLOAN-KETTERING INST CAN RESEARCH. Award amount: 757740.

NIH RePORTEROriginal source
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NIH award: Supporting Families in Coping with Parental Cancer: A Multi-Site Randomized Controlled Trial

Recipient: UNIVERSITY OF TX MD ANDERSON CAN CTR. Award amount: 690715.

NIH RePORTEROriginal source
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NIH award: P3 - Mechanisms of single strand break repair and their regulation by poly(ADP-ribose)

Recipient: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB. Award amount: 327232.

NIH RePORTEROriginal source
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NIH award: Structural Cell Biology of DNA Repair Machine

Recipient: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB. Award amount: 3620769.

NIH RePORTEROriginal source
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NIH award: Investigating the effects of increasing O-GlcNAcylation in Alzheimer's disease

Recipient: UNIVERSITY OF VIRGINIA. Award amount: 88690.

NIH RePORTEROriginal source
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NIH award: Community and digital technology strategy to reduce the burden of HPV and cervical cancer.

Recipient: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO. Award amount: 447610.

NIH RePORTEROriginal source
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NIH award: Dying While Poor: Investigating Multi-level Determinants of End-of-life Care Outcomes for Adults with Heart Failure

Recipient: EMORY UNIVERSITY. Award amount: 142870.

NIH RePORTEROriginal source
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NIH award: Facilitation of Information Exchange for Shared Decision Making for Lung Cancer Screening

Recipient: UNIV OF MASSACHUSETTS MED SCH WORCESTER. Award amount: 74817.

NIH RePORTEROriginal source
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NIH award: Personalizing Clinical Decision Support for Heart Failure Treatment to Clinicians' Needs

Recipient: UNIVERSITY OF COLORADO DENVER. Award amount: 165188.

NIH RePORTEROriginal source
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NIH award: An Intervention to Reduce Cancer Associated Thrombosis Through Improved Prophylaxis

Recipient: UNIVERSITY OF MICHIGAN AT ANN ARBOR. Award amount: 170853.

NIH RePORTEROriginal source
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NIH award: Estrogen's Neuroprotective Effects on the Brain-Barrier in Restrictive Eating Disorders

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 54000.

NIH RePORTEROriginal source
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NIH award: Effect of RCR healing on 5y clinical outcomes and degenerative shoulder changes

Recipient: CLEVELAND CLINIC LERNER COM-CWRU. Award amount: 598929.

NIH RePORTEROriginal source
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NIH award: SCH: AI-empowered Wearable Multimodal Sensors (AI-MEDALLION) for Noninvasive Monitoring

Recipient: OREGON HEALTH & SCIENCE UNIVERSITY. Award amount: 283361.

NIH RePORTEROriginal source
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NIH award: Evaluating patient performance of postoperative incentive spirometry

Recipient: UNIVERSITY OF COLORADO DENVER. Award amount: 304365.

NIH RePORTEROriginal source
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NIH award: Optical Modulation of Quantum Nanomaterial Surface Chemistries to Functionally Mimic Amyloidogenic Protein Assemblies

Recipient: UNIVERSITY OF ROCHESTER. Award amount: 128327.

NIH RePORTEROriginal source
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NIH award: Hippocampal precision mapping to characterize pathophysiology in aMCI and comorbid depression

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 129330.

NIH RePORTEROriginal source
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NIH award: LRRK2-associated mechanisms of granulovacuolar degeneration body formation in neurodegenerative diseases

Recipient: DUKE UNIVERSITY. Award amount: 112406.

NIH RePORTEROriginal source
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NIH award: Improving alcohol treatment outcomes for women across the lifespan

Recipient: BOSTON UNIVERSITY MEDICAL CAMPUS. Award amount: 758464.

NIH RePORTEROriginal source
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NIH award: Project 3: Sex differences in neurovascular and autonomic regulation programmed by fetal immune stress in rodent models

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 407262.

NIH RePORTEROriginal source
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NIH award: Project 1: Impact of prenatal immune dysregulation on sex differences in brainstem connectivity with mood circuitry and neurovascular structure/function in Major Depression

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 638651.

NIH RePORTEROriginal source
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NIH award: Close-kin mark-recapture methods to characterize suppression of Aedes aegypti populations resulting from interventions and extreme weather events

Recipient: UNIVERSITY OF CALIFORNIA BERKELEY. Award amount: 2457639.

NIH RePORTEROriginal source
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NIH award: Role of the ubiquitin independent proteasome system pathway in tau degradation

Recipient: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO. Award amount: 129902.

NIH RePORTEROriginal source
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NIH award: Adapting and Pilot Testing a Relationship Strengthening Intervention to Prevent HIV Acquisition and Transmission among Hispanic Men in South Florida

Recipient: UNIVERSITY OF MIAMI CORAL GABLES. Award amount: 690895.

NIH RePORTEROriginal source
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NIH award: Molecular Pathogenesis and Therapy of Systemic Histiocytic Neoplasms

Recipient: SLOAN-KETTERING INST CAN RESEARCH. Award amount: 550806.

NIH RePORTEROriginal source
๐Ÿ‡บ๐Ÿ‡ธRegulatoryopen.fda.gov

Drug label update: Pregabalin

Official structured record identifier: ab06a36d-9a2d-4eae-8991-4eab5bc8311c.

openFDA Drug LabelsOriginal source
๐Ÿ‡บ๐Ÿ‡ธRegulatoryopen.fda.gov

Drug label update: gabapentin

Official structured record identifier: 4a975ebe-ae0a-446a-8a3d-2ca325e28f93.

openFDA Drug LabelsOriginal source
๐Ÿ‡บ๐Ÿ‡ธRegulatoryopen.fda.gov

Drug label update: unspecified product

Official structured record identifier: 44cd54a7-164b-4006-813d-9e2191e8d0e7.

openFDA Drug LabelsOriginal source
๐ŸŒdiscoverynews.google.com

The Race for the Next Big Weight-Loss Drug Is Onโ€”and China Wants In

wsj.comOriginal source
๐ŸŒResearcheuropepmc.org

Effectiveness and safety of a New Standardised TrEatment Protocol based on initial/early therapy with single-pill combinations of blood pressure-lowering drugs for improving blood pressure control (NewSTeP): Rationale, design of a randomized clinical trial and baseline characteristics of the trial p

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Sex-specific efficacy of acetazolamide for acute mountain sickness. A randomised clinical trial

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Randomized controlled trial comparing 7-day fexuprazan-based and 14-day rabeprazole-based triple therapies for Helicobacter pylori eradication

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

What services do people seek when they visit a community pharmacy care clinic?

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Managing patients with heart failure: A contemporary practice tool for pharmacists

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Medication safety in Indigenous communities: Challenges and interventions

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Ten-year analysis of publications by Quebec hospital pharmacists

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Drug-related problems in older adults with mild cognitive impairment or dementia: A cross-sectional comparison of 2 different instruments

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Management of a patient with a ticagrelorโ€“rosuvastatin interaction: An algorithm-based tool kit for pharmacists

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

A call for the generalist pharmacist

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Spinal muscular atrophy: Biology, pathogenesis, and therapeutic advances.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Herbal Extracts and Plant-Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

FOLFOX-based transarterial infusion chemotherapy for unresectable colorectal cancer: protocol of an open-label, multicentre, randomised, controlled, phase II trial.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Tranexamic acid to prevent anastomotic leak after rectal cancer surgery: protocol for a feasibility trial with embedded mechanistic analysis of the microbiome.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Antibiotic-impregnated bone graft to prevent infection after total hip arthroplasty (ABOGRAFT): protocol for a randomised, double-blind, placebo-controlled trial.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Pharmacokinetics, Safety, and Exploratory Efficacy of Onradivir in Children with Acute Uncomplicated Influenza: A Multicenter, Dose-Ranging, Phase 2 Study.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Heiguteng Zhuifeng Huoluo capsule alleviates osteoarthritis associated with glycerophospholipid metabolism remodeling and PI3K/AKT/mTOR-related inflammatory signaling.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Dose optimization of deuruxolitinib in adults with alopecia areata: A phase 2 randomized trial.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Efficacy of tDCS-primed iTBS in major depressive disorder: A randomized, sham-controlled trial with exploratory resting motor threshold analyses.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Trastuzumab Botidotin Versus Trastuzumab Emtansine in Human Epidermal Growth Factor Receptor 2-Positive Advanced Breast Cancer: A Phase III, Open-Label, Randomized Controlled Trial.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Plasma versus Whole Blood Tacrolimus Concentration and Outcomes After Kidney Transplantation: Post Hoc Analysis of the ALLEGRO Trial.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Association of Cachexia-Related Status With Treatment Outcomes in Advanced Gastric Cancer Receiving First-Line Therapy With or Without Nivolumab.

Europe PMCOriginal source
๐ŸŒResearcheuropepmc.org

Lessons from Cohort Studies of Targetable Metabolic Deficiencies in Lung Cancer.

Europe PMCOriginal source
๐ŸŒResearchdoi.org

Late-Onset Multiple Acyl-CoA Dehydrogenase Deficiency (MADD / Glutaric Acidemia Type IIC) Presenting as Chronic Sensory Ataxic Ganglionopathy, Bilateral Sensorineural Hearing Loss, and Vocal Cord Dysfunction Associated with a Novel ETFDH Variant

CrossrefOriginal source
๐ŸŒResearchdoi.org

Benchmarking Drug Library Compliance and Alert Rates in Smart Infusion Pumps: A Multicenter Retrospective Study

CrossrefOriginal source
๐ŸŒResearchdoi.org

Successful Management of Generalized Drug-Influenced Gingival Enlargement: A Clinical Case Report

CrossrefOriginal source
๐ŸŒResearchdoi.org

Clinical Phenotypes and Factors Associated with Systemic Involvement in Pediatric IgA Vasculitis: A Single-Center Study from Southeastern Tรผrkiye

CrossrefOriginal source
๐ŸŒResearchdoi.org

The Ictal-Interictal Continuum: A Comprehensive Review for the Clinical Epileptologist

CrossrefOriginal source
๐ŸŒResearchdoi.org

The Impact of Medical Procedure in Needle Stick Injuries Among Healthcare Practitioners in Tertiary Hospitals, Rivers State

CrossrefOriginal source