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PharmaRadar360

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Pharmaceutical industry news

Fresh coverage across pharma, biotech, medtech, research, approvals, and market-moving developments.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Target Trial Emulation or Target Trial Approximation?

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Variations of Power Priors in Time-to-Event Analysis With Piecewise Constant Hazards Through Baseline and Outcome Similarity Driven Bounded Weighting.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Power With Confounders in Clinical Trials Using External Controls.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Global Landscape and Thematic Evolution of Selective GLP-1 Receptor Agonists and GLP-1-Based Multi-Receptor Agonists in Type 2 Diabetes Mellitus: A Bibliometric Analysis.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

TITE-LOCRM12: A Local Continual Reassessment Method for Drug Combination Optimization Based on Late-Onset Toxicity and Efficacy Outcomes.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

BEACON: An Adaptive Bayesian Early-Phase Oncology Trial Design Integrating Dose Optimization and Proof-of-Concept Across Survival and Binary Endpoints.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

A Seamless Phase I/II Design With Randomization for Biomarker-Guided Oncology Trials.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Forced Degradation Study of Vonoprazan Fumarate by HPLC and Characterisation of Its Degradation Products Using LC-QTOF-MS/MS.

Europe PMCOriginal source
🌍Researchdoi.orgTier 1 · Research record

First-trimester Detection of Isolated Unilateral Complete Radial Aplasia during Nuchal Translucency Screening: A Case Report

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🌍Researchdoi.orgTier 1 · Research record

Sleep apnea–hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate

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🌍Researchdoi.orgTier 1 · Research record

Pharmacotherapy of heart failure: Impact of the 2021 guideline update on guideline-directed medical therapy assessed using a Japanese employee health insurance claims database

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🌍Researchdoi.orgTier 1 · Research record

Mechanistic Insights and Therapeutic Potential of MCC950 as a NLRP3 Inflammasome Inhibitor in Multiple Sclerosis: A Narrative Review

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Occupational Hazards Faced by Nursing Students in Clinical Training Settings

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🌍Researchdoi.orgTier 1 · Research record

Are there differences in depression across biological sex and developmental phases? Examining the structure and measurement invariance of depressive symptoms in males and females from childhood through adolescence.

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Lessons from the TRIPLET-HCC trial – Authors’ reply

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Accuracy of clinical and radiographic measurements for detecting significant shortening in acute midshaft clavicle fractures: a cross-sectional study with computed tomography scan as the reference standard

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Maternal-offspring microbiome interface contributes to the impact of maternal use of central nervous system-active drugs on offspring neurodevelopment

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🌍Researchdoi.orgTier 1 · Research record

The clinical and genetic profiles, management, and treatment outcomes of familial exudative vitreoretinopathy

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Clinical implications of denosumab discontinuation for spine surgeons

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Inpatient consultations for suspected drug hypersensitivity in children: Diagnostic outcomes of a structured work-up

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Nursing program founders' cross-comparison and synthesis of inclusive excellence for practice readiness: 3 Cs—Curriculum, clinical experiences, culture

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🌍Researchdoi.orgTier 1 · Research record

Reply to the Letter to the Editor on “Temporomandibular disorder and emergency department utilization: demographic, clinical, and economic perspectives from a national database”

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🌍Researchdoi.orgTier 1 · Research record

Experimental and DFT investigation of a novel triazolopyrimidine derivative: Structural, electronic, thermodynamic, and drug-likeness properties

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Reasoning towards endpoints: A two-stage, evidence-augmented method for training-free clinical trial outcome prediction

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Assessment decisions and support for struggling undergraduate nursing students in clinical placements: An integrative review

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Changing epidemiology and etiology of hepatocellular carcinoma in Europe: implications for clinical practice and health policy

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Psychological resilience and psychosocial adaptation in type 2 diabetes mellitus: Associations with executive functioning and clinical indicators

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🌍Researchdoi.orgTier 1 · Research record

Cardiovascular risks in psychiatric disorders and psychiatric risks in cardiovascular disorders: implications for prevention and clinical management – a large-scale umbrella review encompassing 76 meta-analyses

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🌍Researchdoi.orgTier 1 · Research record

Effect of cognitive enhancement therapy for early course schizophrenia on gray matter volume: A confirmatory multisite randomized clinical trial

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🌍Researchdoi.orgTier 1 · Research record

Simultaneous enantioselective separation of 2-, 3- and 4-chloromethcathinones using supercritical fluid chromatography-tandem mass spectrometry and its application to human oral fluid samples

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🌍Researchdoi.orgTier 1 · Research record

Comprehensive profiling of chemical composition, plasma-absorbed prototypes, metabolites, and pharmacokinetics of Jiannao Bushen Pill in rats using UHPLC-MS and microdialysis

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🌍Researchdoi.orgTier 1 · Research record

Quality evaluation of Rhododendri Mollis Flos formula granules by chemical and dissolution fingerprinting using UPLC‑DAD and UPLC‑Q‑exactive orbitrap MS/MS

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🌍Researchdoi.orgTier 1 · Research record

Corrigendum to “Boron and nitrogen-doped coronene as high-performance sensors for gamma-hydroxybutyrate drug sensing: A DFT/TD-DFT study” [J. Mol. Graph. Model. 144, (2026) 109299]

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🌍Researchdoi.orgTier 1 · Research record

Functional polymer-based encapsulation technologies for enhanced probiotic therapeutics

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🌍Researchdoi.orgTier 1 · Research record

Electrospun polymeric nanofibrous scaffolds for potential oral bone and tissue regeneration

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🌍Researchdoi.orgTier 1 · Research record

Molecular insight into hygroscopicity-driven stability in multicomponent piroxicam solid dispersions: Experimental and molecular dynamics studies

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🌍Researchdoi.orgTier 1 · Research record

Development of pH-tunable PLGA nanoparticles for targeted liver delivery of obeticholic acid

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🌍Researchdoi.orgTier 1 · Research record

Can Partial Ins2 Reduction Delay Type 1 Diabetes in a Pre-clinical Model?

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Exploring the Experiences and Perspectives of Participants in a Trial of a Timed Exercise Intervention for the Prevention of Type 2 Diabetes

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🌍Researchdoi.orgTier 1 · Research record

Analytical methods for the determination of semaglutide in pharmaceutical formulations and biological matrices: A comprehensive review

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Clustering of self-reported social and environmental risk factors identifies vulnerable subgroups with increased asthma morbidity

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🌍Researchdoi.orgTier 1 · Research record

3D-printed dual-actuation drug delivery device combining continuous perfusion and iontophoresis

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🌍Researchdoi.orgTier 1 · Research record

Microbiological spectrum of septic arthritis: Diagnostic insights and clinical implications

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Mapping immune cell metabolic reprogramming from mechanistic hotspots to translational directions: A bibliometric analysis with exploratory clinical evidence

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Optimal combination of immune cells for predicting outcomes in ESCC patients following neoadjuvant immunochemotherapy: Results from a prospective phase II trial

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🌍Researchdoi.orgTier 1 · Research record

Corrigendum to “Acidic deep eutectic systems and their capacity to increase drug bioavailability” [Fluid Phase Equilibria 593 (2025) 114332]

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🌍Researchdoi.orgTier 1 · Research record

Biomarkers of chemical- and drug-induced neurotoxicity: A review of mechanistic insights and neuroprotective strategies

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🌍Researchdoi.orgTier 1 · Research record

Species-level reporting of Coagulase-negative staphylococci with MALDI-TOF does not impact clinical outcomes

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🌍Researchdoi.orgTier 1 · Research record

#315 Predictive value of N70 and N20 amplitudes of somatosensory evoked potentials for favorable neurological outcome in post-anoxic coma patients

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🌍Researchdoi.orgTier 1 · Research record

#508 Functional connectivity in patients with juvenile myoclonic epilepsy and healthy controls in Mexican population

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🌍Researchdoi.orgTier 1 · Research record

#380 Chloral hydrate dosing strategies to improve EEG success in children within neurodevelopmental spectrum

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🌍Researchdoi.orgTier 1 · Research record

#176 Experience in the care of patients with amyotrophic lateral sclerosis under the day hospital model

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🌍Researchdoi.orgTier 1 · Research record

#456 Discordance between preoperative motor examination and baseline motor evoked potential findings in spine surgery

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🌍Researchdoi.orgTier 1 · Research record

#253 EEG during Personalized External Aortic Root Support surgery: untangling the effects of cerebral perfusion and anaesthesia

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🌍Researchdoi.orgTier 1 · Research record

#406 Neurophysiologic overlap of amyotrophic lateral sclerosis and limb-girdle myopathy: a case report

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🌍Researchdoi.orgTier 1 · Research record

#479 Physiological biomarkers of risk of Alzheimer’s disease dementia in community-dwelling older people in southern Colombia

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🌍Researchdoi.orgTier 1 · Research record

#407 Optical measurement assessment of motor responses evoked by M1 transcranial magnetic stimulation: A comparison with motor evoked potentials

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🌍Researchdoi.orgTier 1 · Research record

#330 Transcranial focal current stimulation in super refractory status epilepticus in a pregnant patient: A case report

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🌍Researchdoi.orgTier 1 · Research record

Gender disparities across editorial roles in radiology journals; A cross-sectional analysis

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