Pharmaceutical industry news

Early prediction of clinical deterioration in older adults with suspected infection admitted from the emergency department to general wards: a multicenter machine learning study

Growth heterogeneity of Streptococcus suis in host-mimicking conditions is independent of clinical origin

Early Childhood Cumulative Risk and Temperament Predict Preadolescent Appraisal and Coping and Adolescent Psychopathology

Identification of Early Temperament Profiles in Infants at Elevated Likelihood for Autism and Attention-Deficit/Hyperactivity Disorder

Childhood Temperament Types Provide Specificity Over Dimensions in Predicting Early Adolescent Symptoms of Psychopathology: Genetic and Environmental Contributions

Heterogeneity in Callous-Unemotional Traits: Early Temperamental and Environmental Risk Factors in a High-Risk Sample

Effect of DLPFC Targeted rTMS on Phantom Limb Pain and Associated Psychological Comorbidities: A Pilot Randomized Controlled Trial

One-Year Outcomes of M-TEER With the PASCAL System in Atrial and Ventricular FMR: Insights From the MiCLASP Postmarket Clinical Follow-Up Study

Figure 5 from Co-Clinical Evaluation of Synthetic Vitamin D and Chemotherapy in Pancreatic Cancer by Integrated Imaging and Molecular Analyses

Supplementary Figure S4 from Co-Clinical Evaluation of Synthetic Vitamin D and Chemotherapy in Pancreatic Cancer by Integrated Imaging and Molecular Analyses

Supplementary Figure S9 from Co-Clinical Evaluation of Synthetic Vitamin D and Chemotherapy in Pancreatic Cancer by Integrated Imaging and Molecular Analyses

BRIGHTLINE-1: When a Negative Trial Reveals Two Active Therapies

Targeting the <i>Shigella</i> -specific chaperone IpgC in drug development

Bridging the gap: investigating pharmaceutical hydrates through solution spectroscopy

Crystallographic insights into multi-component pharmaceutical solids

Comparison of first attempt success rate of ultrasound-guided internal jugular vein cannulation in supine vs prone position: a prospective randomized controlled trial- PROSPECTUS trial (prone vs supine positioning evaluation for central line insertion using sonography)

Long-Acting Cabotegravir/Rilpivirine in Viremic Individuals: Interpreting Success Beyond Virologic Suppression

Recalcitrant folliculitis decalvans treated with baricitinib or upadacitinib: a case series

Clinical practice patterns and unmet needs in the use of GLP-1 receptor agonists in sleep medicine: A pan-European survey performed in the European sleep apnoea database network

Integrated assessment of pesticides, inorganic ions, and health risks in drinking water from Missal, a rural agricultural municipality in Southern Brazil

Epigenetic mechanisms and clinical translation in ovarian cancer: from molecular pathways to precision therapy

Blood metabolomes distinguish malnutrition and reflect treatment response in adult thalassemia patients: a randomized controlled trial

A system-independent 3D coordinate–based planning method for hexapod deformity correction: a synthetic bone model study and preliminary clinical experience

Conceptualising heart disease prediction through a unified framework combining clinical theory and machine learning models

Drugs Affecting Osseointegration in Dental Implants: Clinical Evidence, Biological Mechanisms, and Implications for Implant Success

Combined Assessment of Estimated Glomerular Filtration Rate and Albuminuria Among Apparently Healthy Young Adults: A Cross-Sectional Study

Can a Smart Ring Improve Sleep? Investigating the Effect of a 4-Week Smart Ring Trial on Sleep Duration and Quality in Middle-Aged Adults

Diagnostic performance of FAPI PET versus ¹⁸F-FDG PET in thyroid cancer: a systematic review and meta-analysis of PET/CT and PET/MRI studies

Analysis and prediction of anti-Chandipura virus molecules as drug and vaccine candidates

Combined microbial inoculation improves plant growth, nutrient acquisition, and soil biological functioning in Opuntia ficus-indica under water deficit

A novel combinatorial therapeutic strategy using resveratrol and viral oncolysis for diffuse intrinsic pontine glioma: an in vitro study

Mechanistic investigation of Juglone (5-hydroxy-1,4-naphthoquinone) as an anti-cancer agent in human colorectal cancer HCT116 and HT-29 cell lines

Unraveling viruses associated with yellowing disease of cucurbitaceous crops in Tamil Nadu (India) through metatranscriptome sequencing

Nanoparticles as catalysts of change: toward third-generation seed technology and stress-resilient crops

Introduction to Special Issue on Collective and Shared Trauma

Clinical evaluation of nnU-Net-based segmentation for enhanced MRCP maximum intensity projection visualization

Resting sympathetic transduction in veterans with PTSD

Guideline-concordant therapy for community-onset pneumonia considering risk factors for drug-resistant pathogens: a propensity score-matched study

Impact of a standardized management protocol and antimicrobial stewardship intervention on mortality and quality of care in Staphylococcus aureus bacteremia: a before-after study

Four-year follow-up on maxillary arch outcomes with presurgical infant orthopedics in unilateral cleft lip, alveolus, and palate: a retrospective cohort study

Exploring sex differences in endocannabinoid system biomarkers and their relationship with antidepressant treatment outcomes in major depressive disorder: a CAN-BIND 1 secondary analysis

Reshaping the Fitness Landscape of Classification Rule Mining for Clinical Natural Language Processing

Catatonia with prominent psychosocial factors: A case report

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

Plantar Angioleiomyoma Masquerading as a Hyperkeratotic Lesion: A Case Report

<scp>BiRD</scp> Regimen Followed by Anti‐ <scp>BCMA CAR</scp> ‐T Cell Immunotherapy as First‐Line Therapy for Newly Diagnosed Multiple Myeloma: A Prospective, Single‐Arm, Phase 2 Trial

Log file‐based patient‐specific quality assurance for MR‐guided radiation therapy with comprehensive motion management

Clinical evaluation of novel deep learning‐based auto‐segmentation software: Utility and potential pitfalls

NCT07786038: E-Health Lifestyle Intervention for Arthritis: A Pilot RCT on Feasibility

Study type: INTERVENTIONAL. Phase: NA.

NCT07785791: ERAS Compliance and Nutritional Outcomes After Lung Cancer Surgery

Study type: OBSERVATIONAL. Phase: .

NCT07785739: Clinical Prediction Model for Disease Progression in Primary Membranous Nephropathy

Study type: OBSERVATIONAL. Phase: .

NCT07785700: Home-Based Functional Electrical Stimulation for Lower Limb Rehabilitation in Stroke Patients.

Study type: INTERVENTIONAL. Phase: NA.

NCT07785648: Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT

Study type: INTERVENTIONAL. Phase: NA.

NCT07785583: Effect of Capacitive Resistive Energy Transfer Therapy on Postmenopausal Women With Frozen Shoulder

Study type: INTERVENTIONAL. Phase: NA.

NCT07785115: Full-Mouth vs. Quadrant-Wise Scaling and Root Planing: Clinical Effectiveness, Environmental Sustainability, and Patient-Reported Outcomes

Study type: INTERVENTIONAL. Phase: NA.

NCT07784816: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Profiles of TLL-018 in Patients With Moderate-to-Severe Atopic Dermatitis

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT07784660: Molecular Imaging of EpCam Expression in Breast Cancer Using [99mTc]Tc-DARPinEc1-G3C

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07784413: A Sequential Trial of Low-Dose Radiotherapy Followed by Concurrent Immunotherapy, Systemic Chemotherapy, and Intraperitoneal Perfusion in Gastric Cancer With Peritoneal Carcinomatosis

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07784335: Pharmacokinetics of Huperzine A Oral Solution in Healthy Participants

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07784283: Integrating HPV Education Into School Health Programs in Cambodia and Kenya

Study type: INTERVENTIONAL. Phase: NA.