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Pharmaceutical industry news

Fresh coverage across pharma, biotech, medtech, research, approvals, and market-moving developments.

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Potential of Plant Derived Products for Antimalarial Combination Therapy

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Individuals with Fragile X syndrome present with associative learning deficits

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Effects of Forest Therapy on Depressive Symptoms: A Systematic Review and Meta-Analysis.

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Findings Interpretation Concerns Regarding the Emulated Target Trial of SGLT2 Inhibitors vs GLP-1 Receptor Agonists in Psoriatic Arthritis [Letter].

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Safety and Efficacy of Remimazolam Combined with Esketamine for Anesthesia in Elderly Patients Undergoing ERCP: A Randomized Controlled Trial.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Diagnostic regulatory pathways are an underrecognized bottleneck in precision oncology clinical trials: Real-world evidence across Europe.

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Precision oncology in breast cancer: Biomarker-driven treatment strategies and the expanding role of APPs.

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Multimorbidity Among Patients Receiving Home Care in Japan: Prevalence, Levels, and Association With Emergency Home Visits.

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Safety of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in USA and Puerto Rico: Results from a Phase III, randomized, active-controlled study.

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From molecular pathogenesis to novel Therapeutic approaches - a review of recent advances in the treatment of peripheral T cell Lymphomas.

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Cutting vs standard balloon for lesion preparation in drug-coated balloon-only PCI: the NATURE randomised trial.

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Health equity in rheumatology-the uneven landscape of cellular therapy.

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Manufacturing Complexity and Scale-Up: Hidden Contributors to Drug Safety Risk.

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Diagnostic accuracy of the passive mast cell activation test in neuromuscular blocking agent-induced perioperative anaphylaxis in a tertiary hospital in China: a diagnostic accuracy study.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Influence of plate type on PBMC-based in vitro cytokine release assays for pre-clinical assessment of cytokine release syndrome.

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Crizotinib versus observation or placebo for surgically resected early-stage ALK-positive non-small-cell lung cancer (Eastern Cooperative Oncology Group-American College of Radiology Imaging Network E4512): a phase 3 trial.

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Molecular targets in proliferative vitreoretinopathy: rethinking prevention, treatment and drug delivery after rhegmatogenous retinal detachment.

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Device-level comparisons of sensing and stimulation in implantable closed-loop neurostimulation for epilepsy.

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Cobrotoxin suppresses TLR4-NF-κB/STAT1 signaling to mitigate glia-mediated neuroinflammation and motor deficits in Parkinson's disease.

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Physiologic Mechanisms of Response to Hypoglossal Nerve Stimulation.

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Glucagon-Like Peptide-1 Receptor Agonist Use and Risks of Hospitalization and Mortality in Patients with End-Stage Kidney Disease.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Ropinirole adjunct to methylphenidate versus placebo adjunct to methylphenidate for attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.

Europe PMCOriginal source
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Statin Use and Arterial Calcification in the General Population: A Longitudinal Analysis and a Negative Control Population.

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AI-powered medicinal chemistry and translational drug development.

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Tailored injectable nanocomposite hydrogels for high-performance biomedical applications.

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🌍Researchdoi.orgTier 1 · Research record

Endoscopic ultrasound-guided lumen-apposing metal stent placement for intra-abdominal abscess management following gastric peroral endoscopic myotomy

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Commuting Dynamics and Their Implications for Physical and Psychological Well-Being of Tertiary Institution Workforce in Kwara State, Nigeria

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Clinical Neuropathology 4-2026

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Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report

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Ultrasound-guided Suprainguinal Fascia Iliaca Block for Postoperative Analgesia in Patients Undergoing Femur Fracture Surgery: A Randomized Control Trial Study Comparing Bupivacaine (0.25%) and Bupivacaine (0.125%)

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Radiographic Evaluation of Distal Femoral Sagittal Morphology Following Imageless Robotic-Assisted Total Knee Arthroplasty Using Functional Alignment

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Artificial Intelligence-Assisted Colonoscopy for Colorectal Lesion Detection: Current Evidence, Challenges, and Future Directions

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Relationship Between Muscle Thickness and Hip and Groin Function in Elite Professional Dancers: A Cross-Sectional Correlational Study

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Determinants of Prolonged Postoperative Length of Stay After Carotid Revascularization: A Single-Center Registry Analysis from Kazakhstan

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Limb Ischemia-Related Interventions and 30-Day Mortality After Femoro-Femoral VA-ECMO: A Pre/Post Implementation-Era Comparison

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Comparison of OneChoice AI-Based Clinical Decision Support Recommendations with Infectious Disease Specialists and Non-Specialists for Empirical Urinary Tract Infection Therapy in Lima, Peru

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Whole Genome Sequencing of the Moruga Hill Rice (Oryza glaberrima) Reveals Its African Ancestry and the Presence of Candidate Stress-Tolerance Genes

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Longitudinal Evaluation of Gingival Margin Modifications During Treatment with Clear Aligners: A Retrospective Clinical Study in Growing Patients

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Independent predictors of clinical outcomes after surgical correction of degenerative lumbar scoliosis: a retrospective cohort study

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Artificial intelligence in infection prevention and control education: toward intelligent, real-time clinical learning systems

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Evaluating air cleaner effectiveness in schools: a comprehensive review and protocol of a cluster-randomized controlled trial of physicochemical and microbial markers

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From seropositivity to neurosyphilis: clinical spectrum and diagnostic classification in hospitalized neurology patients: a 16-year retrospective study

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Prediction of benign paroxysmal positional vertigo recurrence in postmenopausal women: a machine learning-based clinical study

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Clinical and neurophysiological effects of manual acupuncture for upper-limb motor dysfunction after ischemic stroke: a three-arm randomized controlled trial

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Psychotropic dispensing in Greek adolescents and young adults: national trends and regional variation

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Clinical Conditions, Mortality, and Associated Risk Factors in Patients with Flail Chest Injuries: A Tertiary Care Experience

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Determinants of Trust and Reliance on Artificial Intelligence in Clinical Settings: A Study on Physicians’ Use of Large Language Model in Psychiatric Symptom Assessment

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Imaging evidence of osseous fusion of patients undergoing segmental mandibular fibular free flap reconstruction – a retrospective analysis

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🌍Researchdoi.orgTier 1 · Research record

Hypertension, not low-density lipoprotein cholesterol: what a polygenic lens reveals about chronic kidney disease risk

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🌍Researchdoi.orgTier 1 · Research record

Frontiers in noninvasive diagnosis of kidney transplant rejection: from molecular messengers to functional imaging

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Exploring the feasibility of an mHealth intervention delivered by an exercise physiologist within a UK Complications from Excess Weight service: qualitative findings from a randomised controlled trial- MOTIVATE-CEW

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🌍Researchdoi.orgTier 1 · Research record

Response to comments “ Prevalence and clinical predictors of sleep disturbances in children with seasonal allergic rhinitis”

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🌍Researchdoi.orgTier 1 · Research record

Preliminary Real-World Evidence of Clinical and Echocardiographic Changes After Vutrisiran Initiation in Patients With Variant Transthyretin Amyloid Cardiomyopathy in Non-Endemic Regions ― A Single-Center Observational Study ―

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🌍Researchdoi.orgTier 1 · Research record

Clinical Relevance of Atriogenic Tethering in Atrial Functional Mitral Regurgitation

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Impact of Adjusted Creatinine Clearance on Carboplatin Dosing in Endometrial Cancer: A Retrospective Study

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Rethinking pneumonia as a pathway to sepsis: host response and clinical heterogeneity

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Recognizing peer support initiatives organized outside of the clinical setting: insights from a Belgian Delphi method with peer supporters, patients, and mental health professionals

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🌍Researchdoi.orgTier 1 · Research record

Phase IB trial of the BMI-1 inhibitor unesbulin plus neoadjuvant paclitaxel-carboplatin in advanced ovarian cancer

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🌍Researchdoi.orgTier 1 · Research record

KRAS and SKIL mutations synergistically promote pancreatic tumorigenesis through the ubiquitin-proteasome-mediated degradation of Smad4

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🌍Researchdoi.orgTier 1 · Research record

Comparing different techniques of uterine artery occlusion during laparoscopic myomectomy: a randomized controlled trial

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