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🌍Researchdoi.org

Aptamer-Functionalized DNA Frameworks as Targeted Drug Buffers for Concentration Regulation of Maytansine

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🌍Researchdoi.org

An explainable AI framework for early mental health screening and clinical decision support using reflective listening and generative AI

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🌍Researchdoi.org

Trust and the reliability of AI algorithms for clinical decision-making support in medicine: the MIRACLE case study

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🌍Researchdoi.org

Potenzial und Herausforderungen von Large Language Models in der klinischen Entscheidungsfindung

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🌍Researchdoi.org

The deubiquitinating enzyme regulatory network in malignant progression of breast cancer encompasses mechanisms of action, clinical significance and emerging therapeutic targets

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🌍Researchdoi.org

Clinical, Laboratory and Radiological Factors associated with posterior reversible encephalopathy syndrome (PRES) in patients with eclampsia or pre-eclampsia: a systematic review and meta-analysis

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🌍Researchdoi.org

Agreement between artificial intelligence and periodontists in the detection of periodontal bone loss on panoramic radiographs

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🌍Researchdoi.org

Preserving beta cell function in children and adolescents with newly diagnosed stage 3 type 1 diabetes: per-protocol population analysis from the PROTECT randomised trial

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🇺🇸Researchclinicaltrials.gov

NCT07813208: Ph+ ALL in Chinese Children: Diagnosis, Treatment, and Survival

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT07812636: Tirzepatide and Levonorgestrel IUD Therapy for EIN and Early-Stage Endometrial Cancer

Study type: INTERVENTIONAL. Phase: EARLY_PHASE1.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT07812402: The Effect of Factors Affecting Bone Mineral Density Measurement Results on Osteoporosis Diagnosis and Treatment Decision

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT07812142: Retrospective Analysis of the Second Year of Safety Surveillance of the Qdenga® (TAK-003) Vaccine in Private Vaccination Centers, Including a Sub-analysis of Safety in Adults Over 60 Years of Age

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT07811817: The Outcomes of Sympathetic Cardiac Denervation on Postoperative Atrial Fibrillation After Cardiac Surgery, Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07807579: Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure in Adult Traumatic Brain Injury Patients: Randomized Controlled Double-Blind Trial

Study type: INTERVENTIONAL. Phase: PHASE4.

ClinicalTrials.govOriginal source
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NCT07802639: Treatment for "Asymmetric Crying Facies"

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07796880: Neoadjuvant Culmerciclib Combined With Endocrine Therapy for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT07757334: Trauma-Focused Group Therapy for Adults With Trauma-Related Symptoms in Primary Care

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07755800: Impact of an Arginine-containing Toothpaste on the Subgingival Microbiota in Patients in Supportive Periodontal Care

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07619547: Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT07619014: Comparison of the Effectiveness of Miswak and Manual Toothbrush in Removing Dental Plaque in Fixed Orthodontic Patients

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07510737: The Effect of Cross Training on Clinical and Functional Outcomes in Frozen Shoulder Rehabilitation

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT07490925: Transpulmonary Pressure-guided Mechanical Ventilation Strategy in Right Ventricular Protection in Patients With ARDS

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07403487: Phase II Trial of RC1416 Injection in Asthma

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT07346768: Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT07301333: A Study of Single and Multiple Doses of HRS-6257 in Healthy Subjects

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
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NCT07252245: Pre Hospital Triage of Patients at Intermediate and High Risk for ACS

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT07195734: Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT07000253: Timing of Comprehensive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT06991751: A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT06834984: Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06728592: Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06687369: A Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 (Proposed Pembrolizumab Biosimilar) to Keytruda® in Non-small Cell Lung Cancer (BENITO Study)

Study type: INTERVENTIONAL. Phase: PHASE3.

ClinicalTrials.govOriginal source
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NCT06646627: Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
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NCT06595940: Genetic Analysis of Uncommon Disease Presentations in Non-US Populations

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT06485622: Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT06473857: Design, Implementation and Evaluation of an Intervention Within Video Game for Mental Health Literacy in Adolescents and Young Adults

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06360822: Increasing Equity in Lung Cancer Screening

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06345079: Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT06339177: Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT06277401: Exercise in Patients With Hypermobile Joints and Knee Pain

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06040125: Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT06024746: A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Study type: INTERVENTIONAL. Phase: PHASE3.

ClinicalTrials.govOriginal source
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NCT06014827: Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
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NCT05960461: Families Moving Forward (FMF) Connect Pro for Mental Health Providers

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT05726526: CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT05713799: Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT05692687: A Post-market Clinical Study to Evaluate the Safety and Performance of the Carbon Fibre Reinforced Polyetheretherketone Metatarso-Phalangeal (MTP) Plate (CoLink® PCR MTP Plate) for the Treatment of Hallux Rigidus

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT05564390: MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT05413343: Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT05027386: Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II,Multi-center, Clinical Study.

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT04864054: GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
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NCT04288869: Change in Brain Perfusion During Induction of General Anesthesia

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
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NCT03964532: TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
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NCT03952637: A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
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NCT03424005: A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
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NCT03077061: Peri-implantitis - Reconstructive Surgical Therapy

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT01471834: Verification of the Efficacy and Safety of the BAROSTIM NEO System in the Treatment of Drug Resistant Hypertension

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT01426165: Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
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NCT01087320: Genome Medical Sequencing for Gene Discovery

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.gov

NCT01029873: QUILT-2.008: Study of ALT-801 With Cisplatin in Patients With Metastatic Melanoma

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source