Pharmaceutical industry news

Prevalence and Risk Factors of Hypernatremic Dehydration in Exclusively Breastfed Neonates: A Systematic Review and Meta-Analysis

From Pandemic Innovation to Platform Diversification: A Systematic Review of Clinical and Preclinical Development of Non–SARS-CoV-2 mRNA Vaccines

A conceptual clinical reasoning framework for early syndromic recognition in dental practice

Efficacy and predictors of cognitive stimulation therapy combined with pharmacotherapy for mild-to-moderate Alzheimer’s disease: a randomized controlled trial

Editorial: Advances in biomarkers and drug targets: harnessing traditional and AI approaches for novel therapeutic mechanisms

A scoping review of influenza RdRp-targeting inhibitors: mechanisms, clinical translation, and emerging challenges

Early prediction of late-pregnancy hypertriglyceridemia in women with gestational diabetes: development and internal validation of a clinical risk model

Advanced hybrid closed-loop therapy in an older adult with 55-year type 1 diabetes: a CARE-based case report

Mindfulness improves stress and psycho-social morbidities of cancer patients: a clinical trial using community group-therapy in the Indian context

Analyzing The Impact Of Post-Covid-19 Dynamics On Coir Production In Theni District

Optimization, Development and Evaluation of Buccal patch loaded Sitagliptin using natural polymers

Pharmacometric generative stochastic modeling of patient-reported outcome measures

The potential of a selective anxiolytic afobazole in clinical practice

A clinical case of anxiety-hypochondriacal depression with extensive somatized symptoms in the elderly

Clinical efficacy of inosine pranobex in combination therapy of infectious diseases

The effect of Sebia’s CZE IFCC-converted results on carbohydrate-deficient transferrin (CDT) interpretation in driver’s license assessments

Extrapulmonary tuberculosis presenting with proximal esophageal fistula and abdominal lymphadenopathy in a young man: A case report

Retraction: Neoadjuvant Adebrelimab Plus Chemotherapy in Untreated Locally Advanced Head and Neck Squamous Cell Carcinoma: Efficacy and Biomarker Insights From a Single-Arm Phase II Trial

Trends, Patterns, and Demographic Dynamics of Drug Resistance in <i>Mycobacterium tuberculosis</i> and Nontuberculous: A Multi-Year Analysis at the National Tuberculosis Reference Laboratory

Unlocking the scar: ultrasound-guided hydrodissection for post-surgical radial nerve entrapment following clinical plateau

Commentary on “Impact of Computer‐Aided Detection on Endoscopist's Gaze‐Shift Distance During Colonoscopy: A Randomized Controlled Trial”

Interpreting severity in atopic dermatitis: Refining severity bands using clinical trial data

The impact of everyday acoustic environments on chronic pain mechanisms in fibromyalgia: a randomized, triple-blind, placebo-controlled 4 × 4 crossover trial

CUI-Curate: a GraphRAG-based framework for automated clinical concept curation for NLP applications

Dropless after cataract surgery (DACS): concepts, evidence and clinical potential

Maternal and congenital syphilis in Fiji 2019-2022: a secondary analysis of clinical trial data

Unveiling the Best Fit: Comparative Perspective on Animal Models Used for Chronic Diseases

Investigating the Impact of Calcium Channel Blockers on the Pharmacokinetics of Lapatinib: Possible Role of Cytochrome P450 Enzymes and P-glycoprotein Efflux Transporters

Resection of the mesentery vs Kono-S anastomosis in preventing surgical recurrence for primary Crohn disease: the REMEASURE prospective, randomized, controlled trial

Prevention of Acute Enteritis by ZnO Nanoparticles Green-Synthesized using Leonurus japonicus Leaf Extract

Development of a clinical decision support system for exercise prescription among cancer survivors: a modified Delphi study

Dengue and natural products: unveiling nature’s potential in antiviral drug discovery

Long-term analysis of fibrosis in neovascular age-related macular degeneration: A 7-year follow-up

Clinical utility of [18F]-FET PET Imaging in pediatric brain tumors: a case series

Secondary peritoneal leiomyomatosis after uterine leiomyoma intervention: multi-institutional clinical and radiologic experience

What is the risk of HCC in hypervascular LI-RADS 3 observations without ancillary features in routine clinical practice?

Routine circumferential patellar denervation during total knee arthroplasty did not consistently eliminate neural structures at the lateral patellar border: A prospective randomised controlled trial with histological outcomes

Smile beyond Borders: Gender, Academic Level, and Contextual Cross‐Cultural Smile Self‐Perception among Preclinical and Clinical Dental Students

NCT07672314: Bridging the Gap in Psychosocial Care for Cancer Survivors

Study type: INTERVENTIONAL. Phase: NA.

NCT07671989: Period Pills for Menstrual Regulation: A New Reproductive Health Option

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07671963: Bone Substitutes and NIPSA in Intrabony Periodontal Defects: A Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07671898: Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for Bradyarrhythmias

Study type: INTERVENTIONAL. Phase: NA.

NCT07671378: A Study of MRD-Guided Zanubrutinib Plus Sonrotoclax in Treatment-Naïve, High-Risk CLL/SLL Patients

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07671274: Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients

Study type: INTERVENTIONAL. Phase: EARLY_PHASE1.

NCT07671248: Tirzepatide in the Treatment of Cannabis Use Disorder: A Proof-of-Concept Study

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07670741: Community Blood Pressure Screening and Cardiovascular Risk Assessment in Croatia

Study type: OBSERVATIONAL. Phase: .

NCT07666035: Female Sexual Function After Surgery for Benign Perianal Diseases

Study type: OBSERVATIONAL. Phase: .

NCT07622472: Remote Monitoring and Optimization of Heart Failure Therapy

Study type: INTERVENTIONAL. Phase: NA.

NCT07615010: A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07521865: Remote Technologies in Early Stages of Alzheimer's Disease

Study type: OBSERVATIONAL. Phase: .

NCT07425054: ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07361510: A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07255820: Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL Cholesterol

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07140016: A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07063745: A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT06995677: Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT06951698: A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT06726954: Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain

Study type: INTERVENTIONAL. Phase: NA.

NCT05496335: A Study to Evaluate Sequential Administration of AGN-151586 and OnabotulinumtoxinA (BOTOX) Injections in Adult Participants for Treatment of Glabellar Lines

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT05301816: PDN Post Market, Multicenter, Prospective, Global Clinical Study

Study type: INTERVENTIONAL. Phase: NA.