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Fresh coverage across pharma, biotech, medtech, research, approvals, and market-moving developments.

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🌍Researchdoi.orgTier 1 · Research record

Effects of Smart Insole-Based Ground Reaction Force-Biofeedback Training on Muscle Strength, Balance in Patients with Stroke

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🌍Researchdoi.orgTier 1 · Research record

The Spleen Negatively Regulates the Acute Phase of Experimental Autoimmune Encephalomyelitis in Mice

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🌍Researchdoi.orgTier 1 · Research record

Optimizing imatinib sampling strategies through a population approach: a crucial step to model-informed precision dosing validation for point-of-care therapeutic drug monitoring

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🌍Researchdoi.orgTier 1 · Research record

Mapping the Safety Profile of Histone Deacetylase Inhibitors in Children with Cancer

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🌍Researchdoi.orgTier 1 · Research record

Correction: Unintentional benzodiazepine use and frequency of drug checking service utilization: a cross-sectional study

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🌍Researchdoi.orgTier 1 · Research record

KIF23 in disease pathogenesis and therapeutics : from molecular mechanisms to clinical translation

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🌍Researchdoi.orgTier 1 · Research record

Caregiver-led versus therapist-led training programme for caregivers of children with cerebral palsy in rural Malawi: a feasibility randomised controlled trial

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🌍Researchdoi.orgTier 1 · Research record

A randomized clinical trial comparing the efficacy of probiotic drops and sucrose in managing colic in early infancy

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🌍Researchdoi.orgTier 1 · Research record

Retrospective analysis of the clinical characteristics of childhood ocular trauma, 2020–2024

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🌍Researchdoi.orgTier 1 · Research record

Ferroptosis and sepsis-induced myocardial injury: a prospective clinical study

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🌍Researchdoi.orgTier 1 · Research record

Assessing the treatment of male infertility through principal component analysis: a retrospective study

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🌍Researchdoi.orgTier 1 · Research record

Evolocumab in Patients With Prior Percutaneous Coronary Intervention and No Prior Myocardial Infarction: Results From the VESALIUS-CV Trial

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🌍Researchdoi.orgTier 1 · Research record

Lifestyle-Induced Visceral Fat Loss as a Key Target for Durable Cardiometabolic Health: MRI-Assessed 5- and 10-Year Follow-Up After 2 Clinical Trials

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🌍Researchdoi.orgTier 1 · Research record

Blinded trial of multiplex serodiagnostic test in India for diverse forms of active tuberculosis

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🌍Researchdoi.orgTier 1 · Research record

Family Functioning and Medication Self‐Management in Rural Older Adults With Chronic Comorbidities: The Mediating Role of Self‐Efficacy

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🌍Researchdoi.orgTier 1 · Research record

Divergent Radiomolecular Phenotype of Spindle Cell Lipoma​​​​​

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🌍Researchdoi.orgTier 1 · Research record

Developmental Patterns and Clinical Relevance of Os Trigonum, Os Subfibulare, and Os Subtibiale in Young Athletes: A Cross-Sectional Study of 1,167 Athletes

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🌍Researchdoi.orgTier 1 · Research record

Plexiform Neurofibromas and Malignant Peripheral Nerve Sheath Tumors in Adults with Neurofibromatosis Type 1: Clinical Insights from a Large Cohort

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🌍Researchdoi.orgTier 1 · Research record

Prediction of Clinical Outcomes Based on Phenotypic Grouping Using Left Ventricular and Left Atrial Strains in Patients with HFpEF

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🌍Researchdoi.orgTier 1 · Research record

Neurological roots of emotional ambivalence: from brain networks to clinical implications

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🌍Researchdoi.orgTier 1 · Research record

Comment on ‘effects of locally applied water-filtered infrared a irradiation adjunctive to iloprost and carbon dioxide hand baths in patients with systemic sclerosis and severe Raynaud’s phenomenon – a randomized controlled trial’

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🌍Researchdoi.orgTier 1 · Research record

Serum REG3α as a biomarker for clinical and endoscopic activity in ulcerative colitis

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🌍Researchdoi.orgTier 1 · Research record

Green synthesis of tetrahydropyridine-3-carboxylate derivatives and evaluation of antimicrobial and antimalarial activities supported by molecular docking, POM studies, and drug-likeness analysis

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🌍Researchdoi.orgTier 1 · Research record

Robust higher-order feedback feedforward ILC for networked nonlinear system with varying trial lengths, data dropouts and disturbances

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🌍Researchdoi.orgTier 1 · Research record

Bispecific 10E8.4/iMab broadly neutralizing antibody in people with or without HIV-1: a partially randomized phase 1 trial

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🌍Researchdoi.orgTier 1 · Research record

Membrane-anchored DNA nanodevice with allosteric aptamer arms enables parallel probing and on-site drug delivery

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🌍Researchdoi.orgTier 1 · Research record

Empowering clinical trial design with agentic intelligence and real-world data

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🌍Researchdoi.orgTier 1 · Research record

Measurable residual disease is not a universally reliable surrogate for progression-free survival in clinical trials of new chronic lymphocytic leukemia therapies

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🌍Researchdoi.orgTier 1 · Research record

Renal Involvement in Leprosy in the Multidrug Therapy Era: Current Evidence and Clinical Monitoring

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🌍Researchdoi.orgTier 1 · Research record

Genetic control of hypocotyl and ray floret color in newly developed genetic stock PYRS-1 of sunflower and mapping of ray floret color loci using simple sequence repeat markers

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🌍Researchdoi.orgTier 1 · Research record

Complement Component C4B Prioritization Through Drug‒Target Mendelian Randomization and Proteomic Analysis Reveals a Novel Therapeutic Target for Calcific Aortic Valve Stenosis

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🌍Researchdoi.orgTier 1 · Research record

Grafted natural polymers: emerging tools in drug delivery and biomedical applications

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🌍Researchdoi.orgTier 1 · Research record

Multi-method statistical signal aggregation with machine learning for severity classification of neonatal adverse drug reactions

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🌍Researchdoi.orgTier 1 · Research record

From Executor to Orchestrator: The Pharmacology Scientist in the Age of Agentic <scp>AI</scp>

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🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07689019: Effects of Far Infrared Rays and Transcutaneous Electrical Nerve Stimulation on Short Term Prognosis of Head and Neck Cancer Patients Receiving Curative Treatment

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07688980: Study to Characterise Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Anifrolumab Administered Subcutaneously (SC) or Intravenously (IV)

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07688785: Effects of Basic Body Awareness Therapy on Gait and Plantar Pressure in Healthy Young Adults

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07687628: Camera-based Endoscopy Allows Spontaneous Breathing Diagnostic Management in Neonates With Tracheoesophageal Fistula

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07687342: PDCA-Based Precision Nursing for Stroke Patients With Tracheostomy

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07687225: Surgery vs. No Surgery for Primary Tumor in De Novo Stage IV Breast Cancer With Solitary Bone Metastases

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07687186: Qishen Yiqi Dripping Pills in Treatment of Chronic Heart FailUre

Study type: INTERVENTIONAL. Phase: PHASE3.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07651280: Improving the Reliability of LLMs as Medical Assistants for the General Public

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07638397: Orthodontic Treatment Outcomes of Self Ligating System Compared to Clear Aligner System

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07551570: Pharmacokinetics of VC005 Tablets in Subjects With Renal Impairment and Normal Renal Function

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07517211: A Prospective Study of Physical Function in Adults Who Receive Systemic Therapy for Stage I-III Gastroesophageal Cancer, FAST-GO Study

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07512089: Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07447973: Multimodal Deep Learning Model for Multi-task Diagnosis and Triage Suggestions of Ophthalmic Diseases

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07413016: Comparison of Sensory-Adapted and Regular Dental Environments in Patients With Mild Intellectual Disability and Moderate Dental Anxiety

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07406282: A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07396129: Assessing the Efficacy of a High-Dose Lidocaine-Tetracaine Cream for the Treatment of Peripheral Neuropathic Pain

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07345676: Colorectal Cancer Screening Outreach

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07344779: A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07288177: Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07255729: An Exosomal microRNA Signature for Preoperative Staging in Colon Cancer

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07224789: Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07176975: A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT07005154: A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT06964061: Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension

Study type: INTERVENTIONAL. Phase: PHASE1.

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT06857851: Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

Study type: OBSERVATIONAL. Phase: .

ClinicalTrials.govOriginal source
🇺🇸Researchclinicaltrials.govTier 1 · Trial registry

NCT06755736: The Effect of Superficial Cervical Block Application on Postoperative Opioid Consumption in Patients Undergoing Anterior Cervical Discectomy Surgery

Study type: INTERVENTIONAL. Phase: NA.

ClinicalTrials.govOriginal source