Pharmaceutical industry news

Practical Nutritional Strategies to Attenuate Physiological Stress in Adolescent Soccer Players: A Comparative Trial of CoQ10 and Taurine

Implants in Adolescents: Clinical Outcomes After Growth-Pattern-Adapted Implant Placement

Dementia and the Impact of Acetylcholinesterase Inhibitors on Falls, Fractures and Mortality in a Geriatric Cohort: A 4-Year Follow-Up Study

Development and External Validation of an Explainable Machine-Learning Model for Predicting Postoperative Pulmonary Complications in Older Adults Undergoing Degenerative Spine Surgery

Clinical Utility of Repeat Sacroiliac Joint MRI in Patients Evaluated for Axial Spondyloarthritis: A Real-World Cohort Study

Wear-Smile: A Multidisciplinary Telemedicine-Based Smoking Cessation Program Assisted by Wearable Monitoring Devices for Persons Who Smoke—Protocol for a Randomized Controlled Trial

Tobacco Use, Stigma, and Coping in Lung Cancer: A Systematic Review of Their Psychosocial Interactions and Clinical Implications

Optimizing Systematic Endoscopic Lymph Node Staging in Non-Small Cell Lung Cancer: Proposals for Integrating the 9th Edition N-Staging Classification into Clinical Practice

Gonadotropin therapy in idiopathic hypogonadal non-obstructive azoospermia (APHRODITE Groups 3–4): a multicenter randomized controlled trial

Pharmacology education embedded within longitudinal community patient partnerships: an interprofessional approach to medication safety and clinical application

Spontaneous intracranial hypotension with negative brain MRI findings: a systematic review of diagnostic strategies and clinical outcomes

Cell and extracellular vesicle therapies for AKI in critical care: clinical translation, organ-support integration, and lessons learned

A genetic and clinical risk factor algorithm to aid in identifying new cases of chronic kidney disease from the general population

Clinical Evaluation and Management of Pediatric Enuresis: A Study at BMU

Evaluation of Thyroid Disorders in Children with Emphasis on Congenital and Acquired Hypothyroidism

Evaluation of Clinical Profiles, Management Strategies, and Outcomes of Patients with Acute Respiratory Distress in a Tertiary Emergency Department

Impact of Sleep Loss on Neurocognitive Function and Reaction Speed: An Experimental Analysis

Comparative Evaluation of Laparoscopic versus Open Ventral Incisional Hernia Repair

Incidence Patterns, Severity, And Outcomes of Acute Poisoning Cases Presenting to a Tertiary Care Emergency Department

Evaluation of Antidiabetic Drug Utilization Patterns in Type 2 Diabetes Mellitus Patients

Evidence-grounded AI for longitudinal clinical management in musculoskeletal care

Fecal Microbiota Transplantation Improves Clinical Symptoms and Promotes Intestinal Microecological Remodeling in Patients with Constipation Complicated by Anxiety: A Multi-omics Study

Clinical-Prompt-Enhanced Deep Learning Model for Precise Preoperative Prediction of Gallbladder Polypoid Lesion Subtypes

Clinical study evaluating the perioperative combination of duloxetine and pregabalin to improve postoperative pain after mega-liposuction surgery under general anesthesia: a double-blind randomized clinical trial

Association between Denosumab Therapy and Hypocalcemia: Influence of Concomitant Gastric Acid–Suppressive Agents and Other Clinical Parameters

Optimizing high-drug-loaded spray-dried antibody fragment formulations for sustained delivery: influence of excipient composition and humidity on long-term stability

Understanding the small print: a 5-year review of readability in phase I trial information leaflets

Sustained clinical benefit of idursulfase beta in mucopolysaccharidosis II: two-year experience from a phase 3 extension study including patients switched from idursulfase

Effects of 28-day astaxanthin supplementation on psychological fatigue and biochemical markers in taekwondo athletes: a randomized controlled trial

Clinical characteristics and outcomes of critically ill women with gynecologic malignancies: a two-database retrospective study using MIMIC-IV v3.1 and eICU-CRD v2.0

Knowledge improvement on premarital HIV counseling with PAUSE© flipchart versus conventional method: a cluster randomised controlled trial

Therapeutic Drug Monitoring of Linezolid in Real-World Clinical Practice: Determinants of Exposure, Dose Optimization and Hematological Toxicity

Valve Strands in Patients With Infective Endocarditis

Cofactor functions of magnesium in complement activation and antimicrobial responses

Neonatal genetic sequencing as a first-tier option: a real-world clinical implementation study in Northern China

Agentic AI-driven closed-loop analytical systems for autonomous pharmaceutical method development and regulatory-aware analysis

Extracellular synthesis of CeNPs and ZnNPs using thermophilic Anoxybacillus flavithermus and Geobacillus stearothermophilus bacteria, and their biological activities

Breast Conserving Therapy Versus Mastectomy: Outcomes Across Different Clinical Characteristics

Active recruitment for vaccination of patients with solid-organ cancer through the surgical pathway

Deciphering B cell Maturation Dynamics in Hyper-IgM Syndromes

From competence to entrustment: strengthening clinical autonomy within the ESICM educational framework

Domain Knowledge Guided for Varicose Vein Classification with Adaptive Clinical Experts

Diagnostic Pitfalls of Action‐Induced Tremor: A Case Report of Benign Adult Familial Myoclonic Epilepsy Treated with Thalamic Lesioning

Mental Health and Serious Drug Crime: A Case–Control Study

NCT07694219: Bowen Therapy and McGill Stabilization Exercises in Chronic Low Back Pain

Study type: INTERVENTIONAL. Phase: NA.

NCT07692347: Global Myofascial Treatment With Focused Shockwave for Non-Specific Low Back Pain: a Randomized Control Trial.

Study type: INTERVENTIONAL. Phase: NA.

NCT07692230: MRI-Driven Precision Typing and Response Prediction in Luminal Breast Cancer

Study type: OBSERVATIONAL. Phase: .

NCT07691801: Study on the Application of Liquid Chromatography-Tandem Mass Spectrometry for the Determination of Aldosterone and Renin Activity in the Diagnosis of Primary Aldosteronism by Captopril Test

Study type: OBSERVATIONAL. Phase: .

NCT07691515: A Phase III Trial of Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07669363: Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07640191: Feasibility Study of the iVEAcare Neuromodulation System for the Treatment of Drug-Resistant Epilepsy

Study type: INTERVENTIONAL. Phase: NA.

NCT07629440: A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07619495: Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular Risk

Study type: OBSERVATIONAL. Phase: .

NCT07571109: AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07567846: A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.

NCT07545317: Real-World Study of IL-23 Inhibitors in Active Crohn's Disease

Study type: OBSERVATIONAL. Phase: .

NCT07540988: FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07525167: Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data

Study type: OBSERVATIONAL. Phase: .

NCT07520734: Clinical Outcomes After Laser Hemorrhoidoplasty

Study type: OBSERVATIONAL. Phase: .

NCT07421167: A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

Study type: INTERVENTIONAL. Phase: PHASE2.