Pharmaceutical industry news

Targeting the RSV and hMPV L Protein: Cryo-EM and Structure-Based Approaches to Antiviral Drug Discovery

Clinical heterogeneity and diagnostic challenges in CASK-related neurodevelopmental disorders: a longitudinal observational study

Effects of statins on functional capacity and cardiac remodeling in patients with heart failure and preserved ejection fraction: a randomized open-label pilot trial

Clinical Performance of Nitrous Oxide Inhalation versus Intravenous Sedation in Outpatient Dental Surgery: Efficacy and Safety Outcomes

Clinical Efficacy and Safety of 3D Miniplate Fixation for Parasymphyseal and Angle Fractures of the Mandible: A Prospective Study

Prevalence and Clinical Characteristics of Psychodermatoses among Patients Visiting Dermatology Outpatient Department in a Tertiary Level Hospital in Bangladesh

Deep Learning in Chest X-ray Analysis: Advancing Diagnostic Accuracy, Workflow Efficiency, and Environmental Sustainability

High Resolution Computed Tomography Assessment of Pulmonary Artery Diameters in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Comparative Study

Coracohumeral ligament stretching is efficient in enhancing the outward rotation and pain in Adhesive Capsulitis, illustrating relatively better outcomes compared to conventional capsular stretching

Quality by Design-Based Optimization of Betamethasone Dipropionate-Loaded Nanostructured Lipid Carrier Nanogel for Topical Anti-Inflammatory Drug Delivery

A Chromatographic Method Development and Validation for Tofacitinib Citrate and Baricitinib Using RGB And GREEN Pech

Formulation and Evaluation of Lecithin Containing Herbal Cream

A Review on Resmetirom: An Oral Thyroid Hormone Receptor-β Agonist for the Treatment of Metabolically dysfunction-Associated Steatohepatitis (MASH)

Hepatitis B virus in Pakistan: serological marker prevalence, clinical correlates, and genotype-informed interpretation

Self-reported adverse drug reactions to Dolutegravir-Based First-Line Antiretroviral Therapy and associated factors in Ethiopian patients: A Cross-sectional study

Clinical workload dimensions, multidimensional physician well-being, and turnover intention across primary healthcare facilities and hospitals in China: a cross-sectional study

The High-Volume OPD Problem: Why Indian Clinical Documentation Requires a Purpose-Built Artificial Intelligence Model

Drug-of-abuse screening in the era of POCT: a persistent technological gap

La Constitución de 1824 y la extinción de la Fisicatura-mor: impactos en la enseñanza de farmacia y en la fiscalización del mercado de medicamentos

Integrative strategies in herbal product-based Drug discovery: from computational models to molecular insights

The efficacy, safety, and impact of various clinical-pathological characteristics on the adjuvant immune checkpoint blockade in resected melanoma

The glycolysis-H4K12la-PKM2 positive feedback loop drives M2 polarization of macrophages in colorectal cancer

Designing clinical research on hyperbaric oxygen therapy: a narrative review and practical methodological guide

Baseline peripheral blood immune markers associated with clinical outcomes in patients with advanced breast cancer treated with trastuzumab deruxtecan

The impact of spiritual care on gestational diabetes self-management: a randomized controlled trial

Effect of preoperative isometric hand exercise on vascular caliber in patients with advanced chronic kidney disease - a randomised controlled trial

Adaptive Gaussian process search for simulation-based sample size estimation in clinical prediction models: validation of the pmsims R package

A Nomogram for Predicting Buccal Bone Coverage at the Implant Shoulder in Bone Augmentation Using the Full‐Thickness Envelope Flap Technique: A Retrospective Cohort Study

Comment on ‘Lebrikizumab provides stable skin response with no or minimal fluctuations for up to 2 years in patients with atopic dermatitis’

Vibrational Spectroscopy of Clinical Biofluids: Advances in FTIR and Raman-Based Biomarker Discovery for Disease Diagnosis and Monitoring

The role of medium-intensity training in promoting functional independence and cognitive function in older adults: a randomized controlled trial

Drug-tolerant persisters to TRAIL emerge from a dose-dependent surface in a cell-state continuum of sensitivity

Glucagon-like peptide-1 receptor activation and mental health: a drug-target mendelian randomization study

Randomized phase 2 trial of CPX-351 vs. CLAG-M (cladribine, cytarabine, G-CSF, and mitoxantrone) for medically unfit adults with acute myeloid leukemia or other high-grade myeloid neoplasms

Effects of a low-glycemic, moderately-carbohydrate restricted diet on hepatic lipid content and insulin sensitivity in adolescents with MASLD: protocol of a 6-month family-based, randomized controlled trial

Medical Affairs in the Age of Complexity: From Scientific Support to Strategic Enterprise Integrator

Sexual Dysfunction Among Males Living with HIV Receiving Dolutegravir-Based Antiretroviral Therapy in Uganda: A Cross-sectional Study

Phytocompounds with immunomodulatory activities: mechanisms, therapeutic potential, and clinical prospects

Distinct clinical characteristics and prognostic factors of pediatric meningiomas in a 10-year cohort of 198 patients

Flow diversion in proximal superior cerebellar artery aneurysms: Systematic review of clinical outcomes and exploratory hemodynamic analysis

Clinical predictors, microbiological profile, and outcomes of bacteremia in patients with cellulitis: a 6-year retrospective cohort study

Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral

What Counts as Educational Innovation in Clinical Anatomy?

NCT07699835: Efficacy of a Gamified Blended Mindfulness Program to Reduce Burnout, Stress, and Anxiety in Nursing Students: A Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07699562: ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.

Study type: INTERVENTIONAL. Phase: NA.

NCT07699315: Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07699211: Dalbavancin Therapy for Infective Endocarditis

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07698964: A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention

Study type: INTERVENTIONAL. Phase: NA.

NCT07698795: Recovery and Quality of Life in Cervical Cancer Patients Using Vaginal Dilators After Radiotherapy

Study type: OBSERVATIONAL. Phase: .

NCT07698756: A Clinical Study of HRS-8797 in Healthy Participants

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07698457: Clinical Benefit of 18F-FET in Glioma.

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07697560: Safety, Tolerability, and PK of AH-008 Following Single Ascending Dose in Healthy Subjects

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07697105: Effectiveness of the Telemonitoring Program for Patients With Chronic Obstructive Pulmonary Disease (COPD)

Study type: INTERVENTIONAL. Phase: NA.

NCT07697079: Combination of CT and Ultrasound Radiomics Combined With Liquid Biopsy to Predict Neoadjuvant Chemotherapy Response in Patients With Locally Advanced Gastric Cancer

Study type: OBSERVATIONAL. Phase: .

NCT07643272: A Study on the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of HMPL-760 Capsules

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07598708: A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT07567040: Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07526896: Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing

Study type: INTERVENTIONAL. Phase: NA.

NCT07525544: A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07444424: A Study to Investigate the Effect of AZD5004 on Mitiglinide and Pioglitazone in Healthy Participants

Study type: INTERVENTIONAL. Phase: PHASE1.