Pharmaceutical industry news

Inflammatory and Autoimmune Diseases

Deep Vein Thrombosis and Pulmonary Embolism

Arrhythmias

Eco-friendly spectrophotometric determination of moxifloxacin in pharmaceutical dosage form via ion-pair complexation with erythrosine B

NRGN inhibits CD8⁺ T cell effector function by downregulating MHC-I expression through the FMR1–IRF8 axis in hepatocellular carcinoma

Temporal changes in clinical practice and mortality in aneurysmal subarachnoid hemorrhage following the 2012 AHA/ASA guidelines: a retrospective cohort study using the MIMIC database

Histone lysine methyltransferases KMT2C and KMT2D join the all-star tumor suppressor team in gastrointestinal cancer

Targeting hepatic cholesterol sensing to tackle metabolic dysfunction–associated steatohepatitis

Gut microbe–derived short-chain fatty acids regulate alphavirus arthritis and macrophage activation in mice

Branched chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapy

Figure 3 from CAR T-cell Kinetics, Persistence, and Clinical Outcomes in Adult Patients with Relapsed/Refractory B-cell ALL Treated with Obecabtagene Autoleucel in the FELIX Study

Figure 5 from CAR T-cell Kinetics, Persistence, and Clinical Outcomes in Adult Patients with Relapsed/Refractory B-cell ALL Treated with Obecabtagene Autoleucel in the FELIX Study

Supplementary Table S3 from CAR T-cell Kinetics, Persistence, and Clinical Outcomes in Adult Patients with Relapsed/Refractory B-cell ALL Treated with Obecabtagene Autoleucel in the FELIX Study

Supplementary Table S6 from CAR T-cell Kinetics, Persistence, and Clinical Outcomes in Adult Patients with Relapsed/Refractory B-cell ALL Treated with Obecabtagene Autoleucel in the FELIX Study

Enhancing Clinical Diagnosis of Amyotrophic Lateral Sclerosis Through Advanced Prediction and Analysis Using Deep Learning

Photo Quiz: A parsimonious explanation for stacked coins

Combined Left Atrial Appendage Closure and Pulmonary Vein Re‐Isolation in Very‐High Stroke‐Risk Patients

A retrospective cohort study on clinical presentation and surgical management of rectal prolapse at a tertiary care center

Comparative Evaluation of Siemens Atellica and Abbott ARCHITECT Tacrolimus Immunoassays Against LC-MS/MS: A Short Communication

Comment on ‘The reliability and smallest detectable difference of the Severity of Alopecia Tool score in alopecia areata’

Ketamine Versus Propofol for Sedation in Acute Psychiatric Emergencies During Aeromedical Retrieval: A Randomized Clinical Trial

Effectiveness and cost-effectiveness of digital approaches for training frontline health workers in depression care: a randomized controlled trial

Modular in vivo antibody–ADC click to reverse drug resistance in tumours

Pharmaceutical Cocrystals of Febuxostat: Design, Fabrication, Characterization and Bioavailability Assessment

Current evidence on the core components of the geriatric rehabilitation process: a systematic review

Plant growth promotion of rice (Oryza sativa L.) with root endophytic bacteria, isolated from wild Solanaceous medicinal plants Solanum nigrum L., Solanum sisymbriifolium Lam., and Solanum virginianum L.

Microbial inoculation enhances salt tolerance by modulating secondary metabolites and key biosynthetic genes in Melissa officinalis

Matrine suppresses thymoma stemness and apoptosis via YTH N6-methyladenosine RNA binding protein 1 and Wnt/β-catenin signaling

HER2-positive rectal adenocarcinoma metastatic to the pancreas complicated by obstructive pancreatitis and an infected pseudocyst: a case report

AgRP reflects glucocorticoid action: integrated experimental and clinical evidence

The Apelin-APJ Axis in Heart Failure: Mechanistic Insights, Clinical Evidence, and Translational Challenges

Real-world evaluation of primary prophylactic use of granulocyte colony-stimulating factor in patients with metastatic castration-sensitive prostate cancer treated with triplet therapy

Correlation between MRI disc morphology and temporomandibular joint osteoarthritis in patients with temporomandibular joint disc displacement with reduction: a cross-sectional CBCT-MRI combined study

Letter to the Editor Re: “Deep learning models for lumbar spinal stenosis on MRI: model comparison and clinical benchmarking” by Lee et al. (Eur Spine J [2026] 35:548–558. DOI: 10.1007/s00586-025-09443-2)

Timosaponin AIII-based liposomes loaded with Auranofin for the induction of ferroptosis in anaplastic thyroid carcinoma

A Misaligned Multi-modal Clinical Time Series Representation Learning Framework for In-Hospital Mortality Prediction

UGCA-DTI: Uncertainty-Gated Cross-Attention for Robust Drug–Target Interaction Prediction

An Interactive Web Server for Multi-model Drug Repositioning and Evidence Tracing

Predicting Drug Synergy via Cross-modal Contrastive Learning and Masked Multi-omics Hypergraphs

The Expression Patterns of Antibody–Drug Conjugate‐Related Markers in Urothelial Carcinoma With Histological Variants

Anatomy Curriculum and Teaching Insights From Medical Students in the United Kingdom: A National Survey

NCT07706335: Insulin Resistance and Its Association With no Reflow Phenomenon After Primary PCI in Type II Diabetic STEMI Patients.

Study type: OBSERVATIONAL. Phase: .

NCT07705737: Rademikibart IV for Acute Asthma and COPD Exacerbation

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07705620: A Behavioral Digital Intervention For Parkinson's Disease

Study type: INTERVENTIONAL. Phase: NA.

NCT07705607: A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07705321: Assessment of Retinal Microcirculation in Patients With Type 1 Diabetes Mellitus

Study type: OBSERVATIONAL. Phase: .

NCT07705100: Clinical Feasibility Study of Upright, Low-dose, High-resolution, 3D Breast CT (UBCT).

Study type: INTERVENTIONAL. Phase: NA.

NCT07704749: Fitbit-Tracked Micromovement for Cardiometabolic Health in Rural Women

Study type: INTERVENTIONAL. Phase: NA.

NCT07704658: Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07704177: Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07704047: A Clinical Study of FT1 in Patients With Short Bowel Syndrome

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07703176: Clinical and Radiographic Assessment of First Permanent Molars With Cention-N

Study type: INTERVENTIONAL. Phase: NA.

NCT07692841: Single-Dose vs. Divided-Dose G-CSF for Stem Cell Mobilization in Healthy Allogeneic Donors

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07657624: Modifiable Risk Factors for Cognitive Dysfunction in Patients With Coronary Heart Disease

Study type: OBSERVATIONAL. Phase: .

NCT07568249: Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant Treatment

Study type: OBSERVATIONAL. Phase: .

NCT07463443: Effectiveness of Chatbot for Improving Caregiving Outcomes in Primary Caregivers of Geriatric Pneumonia Patients: A Study on Knowledge, Attitude and Practice.

Study type: INTERVENTIONAL. Phase: NA.

NCT07460882: The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension

Study type: INTERVENTIONAL. Phase: NA.

NCT07202104: Improvement of an Algorithm to Detect Structural Heart Murmurs in Adult Patients Using Electronic Stethoscopes

Study type: OBSERVATIONAL. Phase: .

NCT07182721: SKB264 Plus Inetetamab in HER2-Positive Metastatic Breast Cancer Patients Progressing After T-DXd Treatment

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07024615: A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Study type: INTERVENTIONAL. Phase: PHASE1.