Pharmaceutical industry news

CORR Synthesis: Rethinking Value in Orthopaedic Surgery—Why Current Metrics Fall Short

Predictors of Sacroiliac Joint Intervention Following Lumbar Spine Fusion

Individual and Family-Level Risk Factors of Daily Opioid Use in Adolescents Following Spinal Fusion Surgery

Phase 2 Randomized Bivalent RSVpreF Maternal Vaccine Trial: Final Safety, Antibody Persistence and Efficacy

When certainty is lost: Navigating diagnostic uncertainty after specimen depletion

Cutaneous leishmaniasis in patients in treatment with anti-TNF-α drugs. Study of 20 cases from a single institution

Venom induced pressure elevation reversible syndrome: a severe pediatric rattlesnake envenomation, evidence for conservative management, and call for naming the syndrome

Latent variables in cognitive decline: introducing a behavioral-relational factor

Soft contact lens wear in children: benefits and limitations

The Best of Both Worlds — Using Clinical Trial and Observational Data to Evaluate Vaccine Protection

When Celebrities Prescribe — Regulating Drug Promotion on the Internet

Clinical Long-Read Genome Sequencing for Rare-Disease Diagnostics

Decision letter for "Closed-Loop Agentic AI in Drug Discovery"

Effects of cold plasma systems applied to sutures used in third molar surgery on postoperative sequelae and quality of life: a randomized pilot clinical trial

Quantum-classical hybrid learning framework for Parkinson’s disease prediction using acoustic and clinical features

Identification of key clinical features and development of a machine learning model for screening-based detection of diabetic retinopathy

Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial

Oncology drug development in the UK: analysis of the past 25 years and focus on the 2026 reboot of the clinical trial regulatory framework

Dual benefit of esketamine-based opioid-free anesthesia on postoperative pain and mental health outcomes in patients undergoing bariatric surgery: a randomized controlled trial

A 12-week study on the effects of betahistine (an H₃ antagonist/H₁ agonist) on cognitive functions in schizophrenia patients treated with olanzapine.

Malignant self-regard, grit, and perfectionism: A construct validation effort with significant clinical implications.

Supplemental Material for Large Language Models Detect Amplified Abstract Interpretation in Trait Anxiety

Linker Chemistry in Antibody–Drug Conjugates: Current Strategies, Clinical Pharmacokinetic Analyses, and Linker-Free Outlooks

Correction to “Development and Pilot Clinical Study of a Novel FAP-Targeted PET Tracer for PET Imaging of Tumors”

Evolutionary psychiatry in clinical training: findings from a workshop-based educational evaluation

Correction: Clinical, Genetic, and Bioinformatic Insights into a Novel LHB Variant in Isolated Luteinizing Hormone Deficiency: A Case Report

“Hermeneutic burden” and clinical responsibility: a response to Sparrow et al. on explanation and machine learning

GLP-1 receptor agonists and suicidal ideation/behavior: subject-level analysis of clinical trials

Factors Affecting Pharmacokinetics and Dosing Strategies of Polymyxin B in Multidrug-resistant Gram-negative Infected Patients with Renal Impairment: A Systematic Review with Expert Opinion

Beyond Coverage Expansion: Exploring Persistent Barriers to CGM Utilization in the Clinical Environment

Effects of Silica Infused with Gold/Silver/Platinum on the Hepatitis B Drug Entecavir by Theoretical Investigation

Immune checkpoint inhibitor-based chemotherapy for granulocyte-colony stimulating factor-producing advanced esophageal squamous cell carcinoma: a report of three cases

Severe pancreatic exocrine insufficiency presenting with hypoalbuminemia, anasarca, and pulmonary edema in a patient with prior gastrectomy and suspected immunoglobulin G4-related pancreatobiliary disease

Abstracts of the 63rd Annual Symposium of the International Society for Clinical Electrophysiology of Vision (ISCEV 2026), Sydney, Australia

Increased group 2 Innate lymphoid cell (ILC2) activity in pediatric familial mediterranean fever patients with spondyloarthropathy

Integrated bioinformatic evaluation unveils a cellular senescence gene signature as a poor prognostic factor in hepatocellular carcinoma

Cost-effectiveness analysis of chemoradiotherapy compared to surgery in patients with stage I esophageal squamous cell carcinoma in Japan

Real-world study of effectiveness and safety compared among isavuconazole, amphotericin B, and voriconazole in invasive mold disease patients

Synthesis of clinical practice guidelines and recommendations for breast cancer survivorship care: a systematic review

Real-world insights into bone marrow carcinomatosis in metastatic breast cancer: a retrospective analysis from two large university breast cancer centers

Peripheral blood inflammatory biomarkers and response to vagus nerve stimulation in pediatric drug-resistant epilepsy: A retrospective cohort study

Ocular biometry in isolated versus disease-associated high myopia in children and adolescents: A retrospective observational study

CODE.Clinic: A Framework to Promote Health Data Quality and Best Practices for Hospital Clinical Coding

Comment to: Nonoperative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta‐Analysis of Randomized Clinical Trials Comparing Antibiotic Treatment and Appendectomy in Children and Adolescents: “Importance of Prediction Interval”

Unraveling <scp>SPG46</scp> : Clinical, Genetic, and Neuroimaging Features

How does feedback compare with usual care for helping pregnant women stop smoking?

What are the effects of virtual reality (VR) endoscopy simulation training compared with no training or conventional patient-based training?

High‐Density <i>E. Coli</i> Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

NCT07724054: Access to Hygiene in Patients With Dental Implants Using Two Toothbrushes

Study type: INTERVENTIONAL. Phase: NA.

NCT07723950: A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease

Study type: OBSERVATIONAL. Phase: .

NCT07723534: Zolbetuximab With mFOLFOX6 or CAPOX in Claudin 18.2 Overexpressed Advanced or Metastatic Biliary Tract Cancers

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07723469: Phase 3 Trial of SRG-514 Administered Intraoperatively to Patients Undergoing Breast-Conserving Surgery

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07723287: Risk Factors for Drug-Resistant Epilepsy in Children

Study type: OBSERVATIONAL. Phase: .

NCT07723040: Effects of a Nurse-Led Self-Compassion and Kindness Program on Compassion and Healthy Peer Relationships Among Adolescents: A Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07722728: A Study to Investigate Pharmacokinetics, Safety, and Tolerability of B2227 Extended-Release Injectable Suspension and Vraylar® in Participants With Schizophrenia

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT07722715: Randomized, Controlled, Exploratory Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis

Study type: INTERVENTIONAL. Phase: NA.

NCT07722234: Clinical Practice of Hydromorphone in Multimodal Analgesia for Enhanced Recovery After Surgery (ERAS) in Knee Arthroplasty

Study type: INTERVENTIONAL. Phase: NA.

NCT07722156: The Effect of Channa Striata and Curcuma Supplementation on Nutritional Status, Interleukin-6 Levels, and Quality of Life in Patients With Breast Cancer.

Study type: INTERVENTIONAL. Phase: NA.

NCT07721506: A Clinical Trial to Evaluate the Effects of the Edge+Ease PM+AM System on Mood, Mental Clarity, Sleep Quality, and Digestive Wellbeing

Study type: INTERVENTIONAL. Phase: NA.