Pharmaceutical industry news

The CONVERGENCE trial protocol: a phase II/III trial for conversion surgery for gastric cancer with peritoneal metastases

Influencing factors and individualized intervention strategies for inadequate bowel preparation before colonoscopy in high-risk populations: a review based on the clinical practice of painless colonoscopy in China

National trends in cardiovascular deaths with concurrent accidental drug poisoning coding in the United States: a 22-year analysis of the CDC WONDER database (1999–2020)

Convergence of Ancient Wisdom and Modern Healing: The Synergistic Potential of Yoga and Ayurveda in Contemporary Evidence-based Medicine

What Is Your Diagnosis? Cervical Mass in a Timber Rattlesnake

Clinical and Sociodemographic Characteristics of Young People With Early Psychosis: Comparing Cannabis Users and Non‐Users in a Specialized Early Intervention Setting

Evaluating AI demand forecasting models for manufacturing planning in the pharmaceutical sector using AHP and TOPSIS: evidence from literature and a Moroccan case study

Rapid Reinitiation of Clozapine After Recent Discontinuation

Predicting Metabolic Adverse Effects of Lithium in Bipolar Disorder

Impact of system efficiency on out-of-hospital cardiac arrest outcomes and hospital stay: an observational study from Lombardia CARe

Lower STEMI mortality at high volume tertiary centre: Insights from a compact multi-centre region

Keeping It under Control: Developing Reference Materials during a Rapidly Evolving Arboviral Outbreak

Clinical characteristics of ALK-positive NSCLC patients treated with sequential ALK-TKI therapies in a single-centre

Temporal mismatch in allogeneic iPSC therapies: biological risks and implications for clinical translation

Real-world treatment patterns and clinical outcomes among patients with relapsed/refractory multiple myeloma initiating their second, third, and fourth lines of treatment: data from the US Flatiron database

A whole-word computational algorithm for phonological error scoring: Differentiating children with developmental language disorder, hearing impairment, and typical development

Effectiveness of liquorice gel as an adjunct to non-surgical periodontal therapy in chronic periodontitis: a randomized controlled, clinical and microbiological trial

Effect of massed versus distributed preclinical training on subgingival instrumentation skill across the preclinical-to-clinical transition

Supplemental Material for Large Language Model Applications for Real-Time Clinical Mental Health Assessment: Current Potential and Future Directions

Intravenous aprepitant for prevention of postoperative nausea and vomiting in adults at moderate-to-high risk in China: a multicenter, randomized, double-blind, placebo-controlled trial

Therapeutic Potential of Commiphora Species in Wound Healing: A Systematic Review of Clinical Evidence

Correction: The Bidirectionality of Lawyer Reporting Bias in Disproportionality Analysis

Physiologically Based Pharmacokinetic Modeling of Vedolizumab in Healthy Adults and Patients with Inflammatory Bowel Disease

MR-107A-02 in Acute Postoperative Pain Management Following Bunionectomy: Results from a Multicenter, Placebo- and Active-Controlled, Phase 3 Trial

Comparison of induction chemotherapy followed by concurrent chemoradiotherapy versus neoadjuvant chemotherapy followed by surgery and (chemo)radiotherapy in locoregionally advanced hypopharyngeal carcinoma: a prospective cohort study

Clinical and radiographic outcomes of ROSA robotic-assisted total knee arthroplasty: a retrospective comparison of anatomic (persona) versus symmetric (vanguard) implant designs

Biofilm disruption by citronellol and geraniol against clinical uropathogenic Pseudomonas aeruginosa: an integrated in vitro and in silico investigation

Germline pathogenic variants in Japanese adolescents and young adults with advanced solid tumors: a nationwide tumor–normal paired sequencing study

Letter to the Editor: “A kaleidoscopic autoimmune syndrome (COVAS) following COVID-19 exposure”

Evaluation of serum chromium, nickel, and magnesium levels in patients with type 2 diabetes mellitus and periodontitis: A cross-sectional study

Technique-dependent differences in internal adaptation, porosity and degree of conversion of short fibre-reinforced composite restorations in deep MOD cavities

Skin keratin correlates with bone and tendon collagen quality: a proof-of-concept clinical study using FTIR spectroscopy in shoulder arthroplasty patients

The pivotal role of macrophages in tumorigenesis and pioneering cancer immunotherapy across pre-clinical and clinical frontiers

Molecular plasticity of LAMA3 across the disease spectrum: pathogenic mechanisms and clinical translation

Age-, sex-, and segment-specific myocardial T1 and T2 reference values in a healthy cohort: a prospective single-center study

Suizidalität mit instrumentellen Anteilen bei stationärer psychiatrischer Aufnahme oder Entlassung: klinische, ethische und juristische Implikationen sowie Handlungsempfehlungen

Emerging Trends in Artificial Intelligence‐Driven Drug Discovery: Balancing Chemical Design and Pharmacological Properties for Cancer Therapy

Successful Co‐Administration of Secukinumab and Dupilumab in a Patient With Psoriasis and Paradoxical Atopic Dermatitis

Fitness to Stand Trial in India: Demographic, Clinical, and Legal Profiles of Court‐Referred Defendants

Preparation and Characterization of <scp>pH</scp> ‐Responsive Kaolin‐Containing Pectin/Poly(Acrylic Acid) <scp>IPN</scp> Hydrogel for Potential Colon‐Targeted Drug Delivery

World Health Organization Multimodal Improvement Strategy for Hand Hygiene

NCT07729696: Digital Psychoeducational Intervention for Young Adults With Fertility Related Distress Following Cancer Diagnosis

Study type: INTERVENTIONAL. Phase: NA.

NCT07729514: Effect of Different Hyaluronic Acids in the Treatment of Subdeltoid Bursitis

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07729020: Effectiveness of Virtual Reality in Reducing Anxiety and Pain During the First Postoperative Orthopedic Dressing Change in Pediatric Patients

Study type: INTERVENTIONAL. Phase: NA.

NCT07728643: Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Children With Newly Diagnosed Hypertension

Study type: OBSERVATIONAL. Phase: .

NCT07728318: Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients

Study type: INTERVENTIONAL. Phase: NA.

NCT07728188: A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07728136: AI-Guided Mechanical Ventilation in Children: A Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07728019: Efficacy and Safety of Retlirafusp Alfa Plus Bevacizumab and Chemotherapy With or Without Short-Course Radiotherapy in Patients With CRCLM

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07727902: Functional Inspiratory Muscle Training for Gait Recovery in Patients With Chronic Stroke

Study type: INTERVENTIONAL. Phase: NA.

NCT07727642: Optimization of Antiretroviral Therapy in Patients With AIDS-Related Lymphoma

Study type: INTERVENTIONAL. Phase: NA.

NCT07727174: A Clinical Trial Evaluating the Influence of the Ingredients MyCondro™ and Bovine Chondroitin Sulfate on the Behavior of Cells in the Osteoarticular Sphere

Study type: INTERVENTIONAL. Phase: NA.

NCT07725939: A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07725926: Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)

Study type: INTERVENTIONAL. Phase: NA.

NCT07724457: Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT07662148: A Study to Learn More About the Safety of a Single Dose of BIIB144 and How it is Processed in the Body of Healthy Adult Participants Ages 18 to 55 Years Old as Compared to a Placebo

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07513207: A Study in Healthy People to Test How Vicadrostat Affects the Heart

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07494305: Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07367282: Evaluate the Efficacy of Faricimab in Patients With Neovascular Age-related Macular Degeneration

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07363694: A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.