Pharmaceutical industry news

Artificial intelligence in colorectal cancer multidisciplinary decision-making: concordance, predictive support and clinical translation

PIWIL4: from biological characteristics to disease pathogenesis and clinical applications

Secretory carrier membrane protein 3 modulates nuclear ERK1/2 signaling and drug response in triple-negative breast cancer

Medicinal mushrooms and type 2 diabetes: mechanistic insights, translational evidence, and clinical caveats

The clinical effects of probiotic supplementations on metabolic syndrome: a systematic review and meta-analysis

Controlled low central venous pressure after cardiopulmonary bypass reduces acute kidney injury following cardiac surgery: a randomized controlled trial

Immune–microbe interactions in pediatric ulcerative colitis: clinical features, pathogenesis, and novel targeted therapeutic strategies

Immune checkpoint inhibitor-associated arrhythmias: clinical challenges, artificial intelligence-enhanced monitoring, and management strategies

Porous silicon nanoparticles in drug delivery, regenerative medicine, and biosensing: a translational review

Closed-loop non-invasive ventilation in critical care: current evidence and clinical perspectives

Evaluation of Biofertigation for Enhancing Growth and Yield of Blackgram (Vigna mungo L.)

Comparative Phytochemical Screening and In Vitro Anthelmintic Evaluation of Ethanolic and Petroleum Ether Leaf Extracts of Bougainvillea spectabilis Willd. Against Pheretima posthuma

Modified tibial plateau-leveling osteotomy using a precontoured plate achieves single-stage correction with favorable clinical outcomes in small-breed dogs

A Computational Study of Some Cancer Causing S100 Proteins Interacting With a Ligand, Parecoxib and Investigation of Drug Likenes Potential of the Ligand

Pharmaceutical care for patients with leprosy: impact on treatment adherence and pharmacotherapy safety

Development and External Validation of a Machine Learning–Based Clinical Prediction Model for Postoperative Ischemic Stroke in Patients Undergoing Coronary Artery Bypass Grafting: Validation Using the eICU Collaborative Research Database

Associations of pretreatment neutrophil-to-lymphocyte ratio and thyroid-related immune-related adverse events with clinical outcomes in advanced upper gastrointestinal malignancies treated with immunotherapy: a retrospective cohort study

The Effect of Reminiscence Therapy on the Resilience and Satisfaction with Care in Mothers of Premature Infants Hospitalized in Neonatal Intensive Care Units: A Clinical Trial Study

Beta-Lactam Dose Optimization Using Therapeutic Drug Monitoring in Pediatric Patients

Preparation of transdermal patch as a drug delivery system for treatment of urinary incontinence

Interference by saline-based reconstitution of lyophilized quality control plasma in 75 routine laboratory tests

Efficacy and Safety of Celecoxib Combined With Jintiange Capsules for the Treatment of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Clinical significance of resting and dobutamine stress myocardial work in cirrhotic cardiomyopathy

Improving therapist adoption of evidence-based practices with the LOCI strategy: a randomized controlled trial

Analysis of the role experiences of clinical nurse educators in the process of improving the nursing education system

A survey on the current clinical use and perceptions of warm needle acupuncture among Korean medicine doctors

Clinical efficacy and safety of curcumin for the prevention and treatment of radiation injury: a systematic review and meta-analysis of randomized controlled trials

Non-invasive biofeedback-assisted vs. conventional pelvic floor muscle training combined with high-effort resistance training for urinary incontinence after radical prostatectomy: a randomized controlled trial

Post-implementation changes in the procurement volume and patterns of oral hypoglycemic drugs under China’s National Centralized Drug Procurement policy: an interrupted time-series analysis in Shanghai

Clinical characteristics of infective endocarditis in children: a single center of 10-year experience in Beijing

Potential clinical value of miR-122 expression and genetic locus variants in pediatric congenital heart disease

A prognostic model integrating systemic inflammation and clinical features for overall survival in lung cancer: development, internal validation, and external evaluation

Preventability of adverse drug reactions to anticancer drugs: insights from the database of the Regional Drug Information and Pharmacovigilance Center

Association of intraoperative systolic blood pressure variability and clinical outcomes in mechanical thrombectomy: a retrospective cohort study

Advances in drug delivery systems for osteoarthritis therapy: exosomes, microparticles, nanoparticles, and hydrogels

Paired oral clinical specimens reveal the underlying ecology supporting the emergence of inflammophilic microbiome communities

Library strategies differentially shape microbial, functional, and host signals in clinical metagenomic sequencing

Palmar/plantar ligament injuries in five horses: Clinical findings, comparative diagnostic imaging, therapy and outcome

Pseudoangiomatous Stromal Hyperplasia of the Breast: Clinical, Radiologic and Histopathologic Spectrum in a Retrospective Single‐Centre Series

Assessment of pharmacy professionals’ workplace satisfaction in a conflict-affected health system: evidence from Yemen

The future of pharmaceuticals: strategic foresight in an era of uncertainty

Clinical progress in gene therapy for RPGR-associated X-linked retinitis pigmentosa

Hydrogen-Bonded Poly(vinyl Alcohol)/Tannic Acid/Quercetin Hydrogels for Localized Controlled Drug Delivery

<i>In vitro</i> assessments for pharmacokinetic drug-drug interaction potential of vornorexant, a novel dual orexin 1/2 receptor antagonist

Hydrogen-Rich Water Ingestion Alleviates Downhill Running-Induced Muscle Soreness in Recreationally Active Young Men: A Randomized Controlled Trial

NAT10 as a context-dependent epitranscriptomic hub governing cancer drug resistance

Impact of vascular and cardiac parameters on quality of life in patients undergoing catheter ablation for atrial fibrillation

Old drug with new application: spironolactone suppresses Panx 1-mediated Ca2+ influx to attenuate inflammation-driven neutral lipid accumulation in early atherosclerosis

Craniofacial Morphology and Dental Age Assessment in Pediatric Craniosynostosis: A Comparative Cross‐Sectional Study

Environmental Burdens of Long‐Term Cadaver Pool Storage Solutions: A Screening Cradle‐to‐Gate Life Cycle Assessment of Three Formulations

Practical Computational Exploration of Chemical Reaction Space: Assessing the Chemical Stability of Active Pharmaceutical Ingredients Under Acidic Conditions

Neonatal Ventilation Training Using a Low-Cost, High-Fidelity Simulator in a Low-Resource Setting

NCT07819110: Radicle HealthTM VIP: A Study Assessing the Impact of Health and Wellness Products on Metabolic Health and Related Health Outcomes

Study type: INTERVENTIONAL. Phase: NA.

NCT07818395: Spatial Multi-Omics of Perineural Invasion Microenvironment and Prognosis in Prostate Cancer

Study type: OBSERVATIONAL. Phase: .

NCT07818174: Graded Motor Imagery Effects on Body Perception Disturbance in Complex Regional Pain Syndrome : a Randomised Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07817186: Clinical Trial of a MEK Inhibitor for RASopathy-Associated Severe Infantile Hypertrophic Cardiomyopathy: Baby MERIT

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07817004: QLM2010 Comparative Pharmacokinetic Study With 2-Minute Intravenous Administration

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07816731: EFFECT OF FACE-TO-FACE AND VIRTUAL REALITY-BASED SALUTOGENESIS NURSING CARE IN PATIENTS WITH DEMENTIA

Study type: INTERVENTIONAL. Phase: NA.

NCT07816666: Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07815678: First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

Study type: INTERVENTIONAL. Phase: PHASE1, PHASE2.