Pharmaceutical industry news

Moving beyond albumin-adjusted calcium: an indirect reference interval for serum ionised calcium in adults

Reply to the Letter to the Editor: “Antiplatelet Strategy After Drug-Coated Balloon Angioplasty for Isolated Side Branch Lesions: The Missing Piece of the Puzzle”

Perceptions and structural factors of clinical dental hygienists regarding the re-employment of career-interrupted dental hygienists: a qualitative study

Comment on “Interpreting mortality-associated factors after pediatric cardiac surgery: The importance of risk adjustment and clinical context”

Glycemic And Patient-Reported Outcomes After Transition To Advanced Hybrid Closed-Loop System In Patients After Total Pancreatectomy

Adapting to change: when training assessment reform meets clinical reality

MIRRORS-FROZEN: a pilot randomised controlled trial (RCT) comparing open versus robotic surgery in the management of women with complex pelvic adnexal masses ≤ 8 cm—trial protocol

Hybrid trial for alcohol reduction among people with TB and HIV in India (HATHI): protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial

GCMDiff: a condition-guided diffusion framework for pharmacophore-fragment drug discovery and target-specific molecular design

Clinical responses and drug safety of immunotherapy combined with chemotherapeutic regime at first-line in advanced SMARCA4-deficient non-small cell lung cancer: a real-world retrospective study

Treprostinil Inhalation Powder for Pulmonary Arterial Hypertension: Evidence and Clinical Positioning Among Inhaled Formulations

War Criminals on Trial: An Inside View of the International Criminal Justice System, written by Damien Scalia

Pharmaceutical Crystalline Complex of Methylparaben with Active Pharmaceutical Ingredient (API): Preparation, Structural Characterization, and Solid-State Properties

Performance of mCIM/eCIM in <i>Enterobacterales</i> strains co-encoding NDM and OXA-48-like carbapenemases from South India

Burden, Drivers, and Age-related Heterogeneity of Key Components of Cardiovascular-kidney-metabolic Syndrome in China, 1990-2023: A National Burden Analysis with an Exploratory Patient-level Clinical Analysis

Excessive Tidal Volume During Noninvasive Ventilation: Mechanisms of Harm Leading to Worse Clinical Outcomes

Relationships between <i>Schistosoma mansoni</i> infection intensity, environmental enteric dysfunction (EED), and anemia type among preschool-aged children in Uganda

C5aR1 and C5aR2 deficiency confer different degrees of protection against imiquimod-induced psoriasiform dermatitis

Cross-reactive T cell immunity against novel coronaviruses with pandemic potential, predictable from spike sequence conservation

Early treatment of trapdoor deformity after island flap reconstruction using fractional CO2 laser-assisted topical clobetasol delivery. A trick of the trade

Efficacy of electroacupuncture for painful cervical spondylotic radiculopathy and associated changes in cervical biomechanical measures: a study protocol for a randomized, sham-controlled clinical trial

Pharmacotherapy and behavioral treatment for substance use disorders during pregnancy and postpartum: a narrative review

Drug-drug interaction between vonoprazan and imatinib: in vivo pharmacokinetics and in vitro metabolic inhibition characterisation

Resting-state EEG recordings with clinical and medication data from individuals with myotonic dystrophy type 1

Rewired decoding fuels KRAS-driven cancer growth and drug resistance

Beyond conversion: extending the NAPLS-2 risk calculator to predict clinical outcomes in CHR within the CAPR study

Pretransplant Bioconjugation of Renal Endothelial Surfaces for TAK-242 Drug Delivery

Microneedle Patch with Dual Control of Temperature and Drug-Release for Synergistic Chemo-Photothermal Therapy of Melanoma

Hot nights, cold nights, and hypnotic doses: weather as a hidden confounder in mirror-image deprescribing studies

Real-World Outcomes After Switching from Baricitinib to Ritlecitinib in Alopecia Areata: A Multicentre Retrospective Cohort Study

Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial

Effect of implementation of a clinical checklist on the evaluation of constitutional mismatch repair deficiency in a neurofibromatosis clinic

AQbD-based RP-UPLC method for simultaneous estimation of Xanomeline and Trospium chloride in pharmaceutical formulations: development and ICH Q2 (R2) validation

Evaluation of Pharmacokinetic Properties and Drug-Likeness In Silico, Synthesis, and Antiglycation Activity of New N-Hydroxybenzoyl Derivatives of 5-Methylthiazol-2-Amine and 5-Methylthiadiazol-2-Amine

Supporting Children of Parents with Mood Disorders, Anxiety or Substance Use Problems: A Systematic Review and Meta-analysis of Psychosocial Interventions

Very short flow diverters for intracranial aneurysms: technical feasibility, angiographic outcomes, and clinical safety across diverse cerebrovascular locations

A cell‐type resolved proton RBE model for potential clinical application

Motor Cortex Disinhibition Is Dissociated from Clinical Motor Features in Parkinson's Disease: Longitudinal Evidence

Severe Thrombocytopenia Induced by Re‐Exposure to Piperacillin/Tazobactam: A Case Report in Critically Ill Patient With <scp>COVID</scp> ‐19

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

NCT07907705: Arterial Stiffness During Negative Pressure Wound Therapy for Abdominal Wall Wounds

Study type: OBSERVATIONAL. Phase: .

NCT07907419: Effect of a Health Belief Model Based Digital Nudge Intervention on Breast Cancer Screening

Study type: INTERVENTIONAL. Phase: NA.

NCT07907354: Low-Dose Apatinib Plus Chemotherapy in ADC-Pretreated HER2-Positive and HER2-Low Advanced Breast Cancer

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07907289: Adaptive Gamified Sensory Training on Sensory Function and Limb-Specific Functional Performance in Patients With Diabetic Peripheral Neuropathy

Study type: INTERVENTIONAL. Phase: NA.

NCT07907068: Registry of Central Sleep Apnea Patients Undergoing remedē System Implant

Study type: OBSERVATIONAL. Phase: .

NCT07906769: Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence Models

Study type: INTERVENTIONAL. Phase: NA.

NCT07906717: A Study of JNJ-101556143 With Best Supportive Care in Participants With Metastatic Prostate Cancer

Study type: INTERVENTIONAL. Phase: PHASE3.

NCT07906015: Short, Wordless Animated Storytelling to Promote Mental Health Help-Seeking in Young Adults: A U.S. Online Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07904767: A Phase 2 Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07901621: Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b

Study type: INTERVENTIONAL. Phase: NA.

NCT07893938: Perioperative Nutrition Management in Patients Undergoing Open Posterior Lumbar Surgery

Study type: INTERVENTIONAL. Phase: NA.

NCT07872020: SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07724652: The AYA Oncology Self-care Movement

Study type: INTERVENTIONAL. Phase: NA.

NCT07640802: Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy

Study type: OBSERVATIONAL. Phase: .

NCT07617792: [Trial of device that is not approved or cleared by the U.S. FDA]

Study type: . Phase: .

NCT07601815: MEST : A School- Based Health Literacy Intervention Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07574918: Measuring Nasal Airway Changes After VivAer Treatment Using AI Analysis

Study type: INTERVENTIONAL. Phase: NA.

NCT07570173: A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Study type: INTERVENTIONAL. Phase: PHASE2, PHASE3.

NCT07525986: Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07513376: A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

Study type: INTERVENTIONAL. Phase: PHASE3.