Pharmaceutical industry news

Clinical, morphological, and genetic characteristics of children with clear cell sarcoma of the kidney

A Short Review: Liposomes and Niosomes: Advances in Vesicular Nanocarriers for Targeted Drug Delivery

Efficacy of crisugabalin (HSK16149) for refractory chronic cough: study protocol for a randomized, double-blind, placebo-controlled trial

Deployment protocol and base model jointly determine residual risk in rule-based clinical LLM supervision

Clinical characteristics and machine learning-based prediction of postoperative enterocolitis in intestinal neuronal dysplasia: A 20-year retrospective study

Drug-induced isolated lingual hyperkinetic disorder: A case series with review of literature

<i>Stenotrophomonas maltophilia </i>infections – Biofilm-mediated virulence, multidrug resistance, clinical impact, and emerging treatment strategies: A review

Clinical efficacy of combined subhepatic space drainage during laparoscopic cholecystectomy in patients with gangrenous cholecystitis

A liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of vancomycin in human serum and plasma

Genicular artery embolization for refractory pain after knee arthroplasty: clinical outcomes from a retrospective pilot study

Prostate cancer in a family with a germline ATM pathogenic variant: a case report

Development and validation of a critical care practical competency scale for clinical nurses in China

Relationship between 21st century skills and clinical decision-making in Generation Z nursing students: a cross-sectional study

Prevalence, risk factors, and clinical outcomes of hepatitis E infection in pregnant women in Sub-Saharan Africa: a systematic review and meta-analysis

Advances in AI’s Future in Toxicology: Integrating Computational Prediction and Clinical Translation Through Explainable Artificial Intelligence

What are the clinical implications of mixed features in major depressive disorder? A VAST-D report

Reconsidering throat swab culture in melioidosis: diagnostic stewardship with clinical nuance

A comparative performance evaluation of the VIDAS cytomegalovirus (CMV) interferon-gamma release assay (IGRA) and T-SPOT CMV for measuring CMV-specific T-cell responses in allogeneic hematopoietic stem cell transplant recipients receiving letermovir prophylaxis

Currently applied sonication protocols for the detection of implant-associated infections in orthopaedics: a scoping review

Performance of the Techcyte AI-based image analysis system for coproparasitological diagnosis in clinical stool specimens: a retrospective evaluation study

Masking recurrent contaminants in reference sequences improves specificity of clinical metagenomic sequencing

Cost‐effectiveness analysis of total intravenous vs. inhalation anaesthesia among adults aged ≥ 50 y undergoing major non‐cardiac surgery

A Nurse-Led Metamemory-Based Intervention to Improve Medication Adherence in Older Adults With H-Type Hypertension: A Randomized Controlled Trial

Comparison of Epidemiology, Risk Factors, Clinical Presentation and Outcomes of COVID-19 and Seasonal Influenza Among Hospitalized Swiss Children: A Nationwide Prospective Surveillance Study

Oral anticoagulants, cognition, and clinical outcomes in atrial fibrillation and Alzheimer’s disease: a Swedish nationwide study

Accessing treatment against drug use: the biopolitics of methadone across the Georgian–Abkhazian conflict divide

Clinical insights: an update on transmucosal absorption with a focus on dodecyl maltoside

Functional paradigm evolution in microneedle materials: design strategies, performance trade-offs, and translational challenges

Oliceridine used for patient-controlled analgesia on postoperative quality of recovery in patients undergoing laparoscopic gynecological tumour resection: a randomized clinical trial

Long-term storage stability of uracil in plasma

Integrating AI in clinical decision-making

TIM3-targeted delivery of venetoclax overcomes drug resistance and reinvigorates NK cell activity in acute myeloid leukemia

Longitudinal benchmarking of artificial intelligence models for the differential diagnosis of oral mucosal lesions: a controlled clinical validation study

V3-Gemma: an on-device multimodal framework for depression screening through clinical-computational alignment

Clinical translation and engineering challenges of soft robotic cardiac sleeves for heart failure

Cord management in the delivery room: from physiological principles to clinical practice

Effect of bodyweight interval training on frailty status in older adults: a randomized controlled trial

Enhancement of Budesonide Dissolution and In-Vivo Pharmacokinetics via Nanoliposomal Drug Delivery System

Computational Analysis of Peptide Binding on Dengue-Associated Host Proteins POLR2A and Elongin C: Network Pharmacology, Molecular Docking, and Dynamics Simulation Insights

Topical Delivery of Itraconazole by Clove Oil Based Nanoemulgel for Inhibition of 1ZAP Protein in Candida albicans : Formulation, Optimization, In Silico Study, and Antimicrobial Evaluation

Radial shockwave therapy versus short-wave diathermy for pain, neuromechanical, and functional outcomes in older adults with lumbar spondylosis: a randomized controlled trial

Patterns and characteristics of metachronous distant metastases in patients with oral squamous cell carcinoma – A cohort analysis

Reply to: “Comments on ‘The effect of remimazolam versus propofol on respiratory depression for non-intubated general anesthesia: a randomized controlled trial’”

Cross-tissue Mendelian randomization prioritizes RAB27B as a brain-derived candidate protein for postpartum depression

The “obesity paradox” in dosing: a comprehensive analytical review of cockcroft–gault versus CKD-EPI for predicting clearance of narrow-therapeutic-index drugs in patients with BMI > 40 kg/m²

Auditing Implicit Sycophancy in Mental-Health Dialogue: Structured Clinical-State Diagnostics and Clean Matched Benchmarks

From Accuracy to Reliability: AI-Based Respiratory Mechanics Estimation Under Noise and Clinical Variability

Capacity building in medicines development and regulation in Africa <b>—</b> Overview on recent progress

The impact of medication shortages on paediatric care: A retrospective impact analysis

NCT07761884: Early Implementation of Sacral Neuromodulation in Patients With Low Anterior Resection Syndrome.

Study type: INTERVENTIONAL. Phase: NA.

NCT07761572: CS1 Added to Standard of Care Therapy for Pulmonary Arterial Hypertension

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07761169: Randomized Controlled Trial of the SurgDiff Model for Predicting Surgical Difficulty to Help Choose Approach in Mid-Low Rectal Cancer

Study type: INTERVENTIONAL. Phase: NA.

NCT07760961: Effect of Mizagliflozin on Hypoglycemia in Patients With Post-Bariatric Hypoglycemia

Study type: INTERVENTIONAL. Phase: PHASE2.

NCT07760870: Development of a Genetic Score as a Response Modifier for Changes in Weight, Body Composition, and Biochemical Parameters in Obese Adults Undergoing a Low-Energy High-Protein Diet Intervention

Study type: INTERVENTIONAL. Phase: NA.

NCT07760792: Risk Factors and Clinical Implications of Double-J Ureteral Stent Bacterial Colonization

Study type: OBSERVATIONAL. Phase: .

NCT07760675: Evaluating in Person Curriculum for Educating Obstetrical Residents on Better Caring for 2 Spirit Metis Patients Using and AI Assisted OSCE.

Study type: INTERVENTIONAL. Phase: NA.

NCT07760480: Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months of Intensified Treatment With Prednisolone, Mycofenolate Mofetil and Voclosporin as Compared to Mycofenolate Mofetil and Prednisolone

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07760311: Feasibility Study to Evaluate a Digital Tool for Monitoring Patients Who Have Discontinued Treatment for Chronic Myeloid Leukemia

Study type: INTERVENTIONAL. Phase: NA.

NCT07760272: Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy

Study type: INTERVENTIONAL. Phase: NA.

NCT07760155: A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody, ESG206, in Patients With Systemic Lupus Erythematosus

Study type: INTERVENTIONAL. Phase: PHASE2.