Pharmaceutical industry news

Association between abnormal native tibial torsion and poorer clinical outcomes following robotic-assisted total knee arthroplasty: follow-up of at least two years

Enhancing Clinical Decision Support Through Explainable AI: A Comparative Study of CNN and Vision Transformer Models for Skull Fracture Detection in CT Scans

Whole Exome Sequencing in Pediatric Rare Diseases: Genomic Insights and Clinical Utility from single canter Indian Cohort

Floppy Mitral Valve/Mitral Valve Prolapse: Diagnosis and Clinical Classification in This Continuing Odyssey

Exploration of Active Components in Hou-Yan-Qing Oral Liquid and Its Alleviative Effect on Acute Pharyngitis <i>via</i> NRF2/NF-<i>κ</i>B Pathways

11-Oxygenated Androgens in Pcos: Impact of Pcos Phenotypes and First-Line Interventions

Efficacy of perineal massage in second stage of labour for prevention of perineal trauma: a randomized controlled trial

ReVita: home-based transcutaneous auricular vagus nerve stimulation for reducing pathological fatigue in chronic neurological and post-infectious conditions—study protocol for a randomized, double-blind, sham-controlled trial

Pharmaceutical polymer-based hydrogels for 3D bioprinted drug delivery and tissue engineering applications

Unseen emotions, unpaid debts: a qualitative study of emotional exposure and its cumulative emotional consequences in high-intensity clinical settings

Unusual clinical and MRI manifestations of nitrous oxide intoxication: a case report and literature review

Effect of SEEKflex-guided versus conventional intubation on hemodynamic responses in elderly hypertensive patients: a randomized controlled trial

Liposomal bupivacaine versus ropivacaine in four-in-one nerve block for total knee arthroplasty: a randomized controlled trial

Vitreoretinal Lymphoma: A Comprehensive Clinical Review and Current Standards in Management

Multiple-adverse health conditions, mental health, and health-related quality of life in stroke survivors: Latent profile analysis and mediation analysis

Feasibility and acceptability of the breakfast group intervention BISTRo for stroke survivors in acute rehabilitation

Timing of Middle Meningeal Artery Embolization and Surgery: Analysis of the EMBOLISE Trial

At-Home BCI Rehabilitation Therapy for Chronic Upper Extremity Deficit After Stroke (BCI-REHAB): A Randomized Trial

Circulating granulocyte colony‐stimulating factor as a sex‐unbiased global marker of lung and colorectal cancer cachexia pre‐clinical models

Clinical Outcome of Non‐Surgical Endodontic Treatment Performed by Undergraduate Dental Students: A Retrospective Observational Cohort Study

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

Correction to ‘Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase <scp>III</scp> trial’

Development and External Validation of an AI-ECG Algorithm for Estimating Elevated Serum NT-proBNP Levels

Silicon photonic biosensors for clinical diagnostics: system integration and multiplexing strategies

Macrophage heterogeneity in human secondary lymphoid organs

Folic acid–loaded amino-functionalized MCM-41 as a drug delivery system for cervical cancer modulating apoptotic and survival signals

Supplemental Material for Self-Reflection Resilience-Recovery Activity Promotion Training for Emergency Medical Service Clinicians: A Randomized Controlled Pilot Trial of a Novel Digital Intervention

Supplemental Material for Momentary Persistence of Negative Interpretations as a Dynamic Marker of Emotional Distress

Expanding the Biocatalytic Toolbox: A Singular P450 Enzyme Efficiently Produces Diverse Pharmaceutical Metabolites

Radiotherapy-induced immunity is real but incomplete: nano-immunoadjuvants as immune amplifiers in radioimmunotherapy

ELK3‑driven MRP1 upregulation promotes vesicle‑associated drug efflux and chemoresistance in GBM

Does Route of Administration Matter for Gepant Safety? A Comparative Disproportionality Analysis of Intranasal Zavegepant Using the FDA Adverse Event Reporting System

Sphingosine-1-Phosphate Signaling and Nanocarrier-Based Topical Therapeutics in Plaque Psoriasis

Design and Optimization of Hydroxypropyl Beta-Cyclodextrin-Based Miconazole Nitrate Nanosponges Gel for Enhanced Transungual Drug Delivery

Antimicrobial and Anti-inflammatory Potential of Thermoresponsive In situ Gel Loaded with Metronidazole Microsponges for Localized Treatment of Periodontitis

Harnessing Kruppel-like Factor 4 for Glioblastoma Immunotherapy: A Multiepitope Subunit Vaccine Design Approach

Autoinflammatory Syndromes of Hidradenitis Suppurativa: Updates in Clinical Features, Emerging Associations, and Management

Reduction in extraocular muscle and orbital fat volumes after teprotumumab treatment in Japanese patients with thyroid eye disease: an exploratory magnetic resonance imaging analysis from the OPTIC-J trial

Three-dimensional spatiotemporal analysis of condylar remodeling after conservative treatment of pediatric mandibular condylar sagittal fractures

Dose- and time-dependent biochemical, histopathological, and genomic effects of chronic carbonated beverage consumption in rats

Enriched trial designs and the patients left behind

Prenatal Genomics for Sonographers: Enhancing Confidence, Communication, and Clinical Care

Uterine Artery Doppler Disturbance Index Is Associated with Endometrial Perfusion and Clinical Pregnancy in <scp>IVF</scp> / <scp>ICSI</scp>

Congenital short bowel syndrome: Clinical aspects by systematic review

A Practical and Efficient Multiplex <scp>qPCR</scp> Assay for Simultaneous Detection of <scp>HLA</scp> Cross‐Reactive Groups and Human Platelet Antigens

Clinical outcomes associated with <i>NPM1</i> mutations in newly diagnosed acute myeloid leukemia

Correction to “Efficacy and safety of teclistamab in triple‐class exposed relapsed/refractory multiple myeloma: Pooled findings from three clinical cohorts and a retrospective cohort”

SCORE‐CUT: A Randomized Trial Comparison of Scoring, Cutting, and Non‐Compliant Balloon Lesion Preparation Strategies for Drug‐Coated Balloon Angioplasty—Rationale and Design

Application of <scp>3D</scp> ‐Slicer combined with <scp>3D</scp> printing technology in training neurosurgery resident physicians' imaging spatial cognition and clinical reasoning: A self‐controlled before‐ and after‐study

NCT07764081: Progression, Management, and Clinical Outcomes of Coronary Artery Aneurysms

Study type: OBSERVATIONAL. Phase: .

NCT07763821: Clinical Utility of Serum Ribonuclease 1(RNASE1) as a Biomarker of Lupus Nephritis.

Study type: OBSERVATIONAL. Phase: .

NCT07763665: Anti-inflammatory Effect of MgSO₄ in Patients With Moderate Traumatic Brain Injury by Measurming Nucleotide-binding Oligomerization Domain-Like Receptor Pyrin Domain-containing 3 (NLRP3) Inflammasome-a Multiprotein Complex

Study type: INTERVENTIONAL. Phase: PHASE4.

NCT07763340: Photon-Counting Cardiac CT in Post-PCI Patients

Study type: OBSERVATIONAL. Phase: .

NCT07763275: Autologous Nanofat for Treatment of Atrophic Scars

Study type: INTERVENTIONAL. Phase: NA.

NCT07763184: mNGS for IFD in Patients With Hematological Malignancies

Study type: OBSERVATIONAL. Phase: .

NCT07762781: Impact of a Mobile Exercise Application on Sleep, Pain, and Fitness in Healthy Adults

Study type: INTERVENTIONAL. Phase: NA.

NCT07762599: Silver Nanoparticle-Reinforced Double Antibiotic Paste in Symptomatic Apical Periodontitis: A Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07762378: Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic Therapy

Study type: INTERVENTIONAL. Phase: NA.

NCT07762105: Study of Atorvastatin and Its Effects in Clinical and Radiological Aspects in Patients With Moderate-to-Severe Thyroid Eye Disease

Study type: INTERVENTIONAL. Phase: PHASE1.

NCT07761988: The FamilyStrong Pilot Randomized Trial

Study type: INTERVENTIONAL. Phase: NA.