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Pharmaceutical industry news

Fresh coverage across pharma, biotech, medtech, research, approvals, and market-moving developments.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

The mitophagy-inflammasome axis: a shared pathological hub in Alzheimer's and Parkinson's diseases.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Falls in older patients treated for cancer in French outpatient departments: screening and prevention-a prospective observational study.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Pharmacokinetics, safety and preliminary efficacy of conbercept eye drops for corneal neovascularization: Results from phase I/IIa studies.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Unsaturated fatty acids enhance metabolic flexibility by accelerating time-based RQ dynamics.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Gut microbiome crosstalk in acute myeloid leukemia: mechanisms, treatment-associated dysbiosis, and translational opportunities.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Assessment of Virtual Digital Articulation Versus Hand-Articulation Accuracy for Occlusal Registration in Orthognathic Surgery (A Randomized Clinical Trial).

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Reducing the diagnostic and treatment gap for priority mental, neurological and substance misuse disorders in primary care in rural Kenya: Results of a stepped wedge cluster randomized trial from the EPINA study.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Safety of Antiseizure Medications During Direct Oral Anticoagulant Therapy in Epilepsy.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Therapeutic drug monitoring in children and adolescents treated with quetiapine for different psychiatric disorders: results of the TDM-VIGIL pharmacovigilance study.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Reframing kidney outcomes in CKD trials: eGFR slopes, competing risks, and pragmatic trial design.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Cost-utility analysis of trastuzumab deruxtecan versus trastuzumab emtansine as second-line treatment for HER2-positive metastatic breast cancer.

Europe PMCOriginal source
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Cost-effectiveness analysis of anlotinib plus Penpulimab as first-line treatment for unresectable hepatocellular carcinoma.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Final 2-Year Results of the REFORM Study: A Randomized Trial of Biolimus DCB Versus Paclitaxel DCB for In-Stent Restenosis.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Effectiveness of Multidomain Cardiac Rehabilitation After Myocardial Infarction by Patient Frailty: Prespecified Subgroup Analysis of the PIpELINe Trial.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Simultaneous quantification of seventeen kratom alkaloids and metabolites in human plasma and its application to clinical pharmacokinetic sample analysis.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

A DAR sensitive hybrid LBA-LC-MS/MS assay for quantitation of conjugated payload from a non-cleavable ADC in human serum.

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🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Efficacy of Luseogliflozin Added to Semaglutide in Patients With Metabolic Dysfunction-Associated Steatohepatitis and Type 2 Diabetes Mellitus: A Randomised, Open-Label Trial.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Fatty Liver Index and Differential Glycemic Responses to Ipragliflozin Versus Sitagliptin Over 52 Weeks: An Exploratory Post Hoc Analysis of the Niigata Ipragliflozin and Sitagliptin With Metformin (N-ISM) Study.

Europe PMCOriginal source
🇪🇺Researcheuropepmc.orgTier 2 · Direct publisher

Pharmacokinetic and pharmacodynamic sub-study of trans-arterial vs. intravenous gemcitabine in the TIGeR-PaC phase 3 clinical trial.

Europe PMCOriginal source
🌍Researchdoi.orgTier 1 · Research record

Clinical Skills and Moral Sensitivity among Student Nurses during Patient Care: A Critical Integrative Review through the Lens of Nel Noddings’ Ethics of Care

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🌍Researchdoi.orgTier 1 · Research record

Leptospirosis/Weil's Disease: Pathogenesis, Epidemiology, Bio-Screening, Next-Generation Interventions Powered by AI, ML, Modeling, 3d Fingerprinting, Cover Etiology, Treatment Horizons, Fungal, Mosquito and Airborne Infection

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🌍Researchdoi.orgTier 1 · Research record

Artificial Intelligence-Powered Translational Nanomedicine in Oncology: Clinical Developments, Multistage Targeting Techniques, And Prospects for Brain, Liver, Breast, and Kidney Cancers

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🌍Researchdoi.orgTier 1 · Research record

ML in Rare Facial Disorders: Hemifacial Microsomia, Parry-Romberg Syndrome, Moebius Syndrome, Treacher Collins Syndrome, Apert Syndrome, and Crouzon Syndrome-From Etiological Mapping and Pathology to AI-Driven Bio-Computational Gene Therapy

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🌍Researchdoi.orgTier 1 · Research record

Artificial Intelligence-Driven Translational Nanomedicine in Oncology: Multistage Targeting Strategies, Clinical Advances, and Future Directions for Liver, Breast, Kidney, and Brain Cancers

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🌍Researchdoi.orgTier 1 · Research record

Rare Malignancies: Appendix Cancer: AI- Driven Histopathology and Molecular Biomarker Integration in Biopsy, Chemotherapy, and Immunotherapy Trajectories

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🌍Researchdoi.orgTier 1 · Research record

Evaluasi Pola Peresepan Dan Drug Related Problems Pada Pasien Tuberculosis Paru Di Poliklinik Paru Rumah Sakit Umum X Di Purbalingga

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🌍Researchdoi.orgTier 1 · Research record

Artificial Intelligence in the Optimisation of Glucagon-Like Peptide-1 Receptor agonist Therapy for Obesity and Type 2 Diabetes: A Critical Narrative Review of Treatment Monitoring and Clinical Decision Support

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Medicinal Plants and Human Cognitive Health: A Critical Appraisal of Mechanistic Plausibility, Clinical Evidence and Translational Constraints

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🌍Researchdoi.orgTier 1 · Research record

Fentanyl-induced chest wall rigidity in critically ill patients: A report of two cases

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🌍Researchdoi.orgTier 1 · Research record

Peer Review Report For: Artificial Intelligence Integrated with Intraoral Digital Imaging in Dental Caries Detection, Treatment Planning, and Clinical Decision-Making: A Scoping Review [version 2; peer review: 2 approved, 1 approved with reservations, 1 not approved]

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🌍Researchdoi.orgTier 1 · Research record

Feasible Safe Disposal Strategies that Can Be Used to Manage Pharmaceutical Waste among Households in Nakuru City

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🌍Researchdoi.orgTier 1 · Research record

Inorganic nanoparticles for targeted drug delivery in theranostics: A review of applications, methods, and biomarkers for quantification

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🌍Researchdoi.orgTier 1 · Research record

The impact of change management on the well-being of medical staff of different generations at the Children’s Clinical University Hospital Ambulatory Health Center

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🌍Researchdoi.orgTier 1 · Research record

Margetuximab: An Updated Review of its Clinical Pharmacology and Therapeutic Advances

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🌍Researchdoi.orgTier 1 · Research record

Synergistic attack of “old drugs for new uses”: repositioning strategies in cancer combination therapy

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🌍Researchdoi.orgTier 1 · Research record

Synchronizing obesity management with survodutide

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🌍Researchdoi.orgTier 1 · Research record

Orthogeriatric Fracture Syndrome: Time Is Mobility!

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🌍Researchdoi.orgTier 1 · Research record

Development and Validation of a Simplified Five-Variable Score for Predicting Massive Transfusion in Blunt-Trauma-Predominant Patients

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🌍Researchdoi.orgTier 1 · Research record

Discordance Between Clinical Suspicion and Spirometry-Defined Reversible Airflow Obstruction in Children with Sickle Cell Disease in French Guiana

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🌍Researchdoi.orgTier 1 · Research record

Clinical Outcomes and Factors Associated with MACCE in Chinese Patients Undergoing Single-Hospitalization PCI and Transfemoral TAVR

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🌍Researchdoi.orgTier 1 · Research record

Development and Laboratory Evaluation of a porA-Targeting TaqMan qPCR Assay for Neisseria gonorrhoeae: Clinical Specimen Validation and Molecular Estimation Using Cultured Reference Strains

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🌍Researchdoi.orgTier 1 · Research record

Correlation between clinical variables and overall survival time in dogs with multicentric B-cell lymphoma: a retrospective study in Taiwan

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🌍Researchdoi.orgTier 1 · Research record

SPRTN preserves RNA polymerase I transcription under genotoxic drug stress in lung adenocarcinoma

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🌍Researchdoi.orgTier 1 · Research record

Effects of an intensive pulmonary rehabilitation program on postoperative pulmonary complications in frail elderly patients undergoing hepatobiliary and pancreatic surgery: a randomized controlled trial

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🌍Researchdoi.orgTier 1 · Research record

Dissecting and stimulating instruments in thyroid surgery: principles, applications and clinical role

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🌍Researchdoi.orgTier 1 · Research record

Assessment of drug allergy and determination of safe alternative medications: a retrospective observational study

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🌍Researchdoi.orgTier 1 · Research record

The COPD-driven “lung–eye axis”: mechanisms and clinical evidence of ocular disease

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🌍Researchdoi.orgTier 1 · Research record

Warm acupuncture combined with precise meridian sinew needling for refractory peripheral facial paralysis: a propensity score-matched retrospective study on clinical efficacy and infrared thermal imaging

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🌍Researchdoi.orgTier 1 · Research record

Calcitonin gene-related peptide as a neuroimmune amplifier in allergic rhinitis: from disease worsening to targeted drug intervention

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🌍Researchdoi.orgTier 1 · Research record

Ultrasound-guided continuous parasacral ischial plane block for diabetic foot ulcer healing: study protocol for a single-centre, prospective, randomised, open-label, blinded-endpoint controlled trial

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🌍Researchdoi.orgTier 1 · Research record

Urinary tract infections in diabetes: clinical significance and management approaches

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🌍Researchdoi.orgTier 1 · Research record

Functional abdominal pain disorders: Prevalence, clinical and socio demographic profile

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🌍Researchdoi.orgTier 1 · Research record

EVALUATION OF STRESS MANAGEMENT IN VETERINARY CLINICS IN TERMS OF ANIMAL HEALTH AND CLINICAL MANAGEMENT

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🌍Researchdoi.orgTier 1 · Research record

Nutraceutical and Functional Evaluation of Corn Silk Extract as a Natural Antioxidant in Dairy Dessert Formulations

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🌍Researchdoi.orgTier 1 · Research record

Strategic enterprise risk management and operational resilience in China’s pharmaceutical industry: A comparative analysis

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🌍Researchdoi.orgTier 1 · Research record

Quality by Design (QbD) Framework for Manufacturing Peptide-Drug Conjugates

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🌍Researchdoi.orgTier 1 · Research record

Molecular Characterization and Genotypic Distribution of Hepatitis B Virus Isolates in Iraq: Prevalence of Drug Resistance Mutations

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🌍Researchdoi.orgTier 1 · Research record

Emerging physiotherapy interventions for sarcopenia: A comprehensive evidence review

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🌍Researchdoi.orgTier 1 · Research record

Impact of an online educational webinar on awareness, clinical confidence, and perceived barriers in the management of congenital hyperinsulinism in India: A cross-sectional survey

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🌍Researchdoi.orgTier 1 · Research record

What's in a name? Etymology as an adjunct to anatomical teaching

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