Pharmaceutical industry news

Clinical characteristics of patients with late-onset systemic lupus erythematosus with a disease onset of ≤ 3 months

Scaling MOUD Implementation in Correctional Settings Through a Digital Coaching Platform: A Mixed-Methods Pilot

Hyperreflective Choroidal Foci Characterization Supports the Existence of Different Clinical Phenotypes of Geographic Atrophy

PF-08046876, a Differentiated Integrin Beta-6 Antibody–Drug Conjugate Delivering a Potent Camptothecin Payload Optimized for Bystander Effect and Reduced Drug Efflux

EMB-01, an Anti-EGFR/c-MET Bispecific Antibody, in Patients with Heavily Pretreated Metastatic Colorectal Cancer From a Phase Ib/II, Open-Label, Multicenter Study

Elacestrant in Combination with Everolimus for Estrogen Receptor-Positive, HER2-Negative Previously Treated Advanced Breast Cancer: Results from ELEVATE

Machine Learning-Based Classification of Lower Urinary Tract Symptoms from Uroflowmetry: Evaluation Against Physician Decisions and Clinical Nomograms

Evaluating the impact of a training module for pre-professional health students in the delivery of clinical prevention and physical activity behaviour change

Treatment discontinuation after complete response to BRAF/MEK inhibition in metastatic melanoma: long-term clinical outcomes from a single institution

Between hypersensitivity and toxicity: the complex spectrum of chemotherapy-induced skin reactions

Lesson for the clinical nephrologist: Acute kidney injury unmasks subclinical Sheehan’s syndrome

Cardiac rehabilitation programme accreditation and certification: Comparing international practices, mapping standards, benchmarks, and future directions – A scoping review

Ramifications of Biological Variability on Tests for Primary Aldosteronism Screening

From “cluster imitation” to “first generic”: the impact of market exclusivity incentives on Chinese generic drug manufacturers

A qualitative inquiry into the environmental barriers and facilitators to non-specific low back pain clinical practice guideline adherence among Canadian physiotherapists

Reading Sachs: <i>Black Hamlet</i> on Trial

Appointment adherence, weight reduction, and retention at 9 months in Australian clinical obesity services: a retrospective cohort study

Targeting drug delivery technologies

Prospective randomized controlled study on the hybrid teaching model in urological clinical nursing education under the digital background

multiGMF: A multi-similarity geometric matrix factorization for identifying drug-associated indications

Prevalence and clinical characteristics of dermatophytosis in rheumatoid arthritis according to DMARD therapy

A longitudinal plasma metabolomics dataset of sepsis-associated liver injury across multiple clinical time points

Towards precision psychiatry: initial foundations and future directions

Circulating Matrix Metalloproteinase Activity and Functional Capacity in Individuals Undergoing Hemodialysis: Exploratory Findings from a Resistance Training Trial

An Unusual case of Alternaria Alternata Onychomycosis in an Immunocompetent Patient: Case Report and Review of the Literature

Prevalence and Associated Factors of Potential Drug–Drug Interactions Among Older Hospitalized Patients with Chronic Conditions in Pakistan: A Cross-Sectional Study

AI and Digital Health in the Diagnosis, Prediction, and Treatment of Migraine: Current Applications and Future Perspectives

Non- and minimally invasive management of hypersensitivity in molar-incisor hypomineralisation (MIH) at home and in clinical practice: a systematic review

Clinical Profile, Surgical Approaches, and Prognosis of Lateral Ventricular Tumors: ambispective Experience from a Tertiary Care Center

Formulation and In vitro Characterization of Rosuvastatin Calcium Loaded Chitosan Nanoparticles for Sustained Drug Release

Evaluation of a Novel Isothermal Microcalorimetry-Based Sterility Test

Formulation, Optimization, and Evaluation of Gastro-Retentive Floating Beads of Nelfinavir Mesylate Prepared by Emulsion Gelation Technique

Targeting ferroptosis to overcome drug resistance in gastrointestinal cancers

Predictors of Treatment Success Following Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion: A Multivariable Prediction Model with Clinical Nomogram

Minimal Residual Disease in Head and Neck Cancer: Molecular Surveillance and Clinical Action

Efficacy and safety of intraperitoneal lidocaine in patients undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized clinical trials

Cobalamin C Deficiency Presenting with CVID-like Immunologic Abnormalities: A Five-Patient Pediatric Case Series

Diagnostic Utility of FAS Sequencing in Suspected ALPS: Insights from a Large Clinical Cohort

Multimodal graph neural networks for integrating heterogeneous medical data in clinical decision making

Primary outcomes of a phase II trial of laparoscopic/robotic total gastrectomy with spleen-preserving splenic hilar dissection for locally advanced proximal gastric cancer involving the greater curvature (JCOG1809)

Mechanism-informed combination therapy and dynamic risk stratification in lupus nephritis: toward durable renal protection

Letter to the editor: Protocol to improve quality of life, functionality, and exercise capacity in patients with axillary web syndrome after breast cancer: a randomized clinical trial

CRISPR/Cas9 knockout of N-acetyltransferase 1 influences mesenchymal transition in glioblastoma in a cell line dependent manner

5-year outcomes of iStent micro-bypass vs. Kahook dual blade goniotomy in open angle glaucoma

Association between systemic conditions and the development of glaucoma in a longitudinal large-scale health examination cohort

Quantifying the inclusion of cardiovascular research into clinical guidelines

Stress CMR versus SPECT for the detection of coronary artery disease: meta-analysis and implications for the German healthcare

Late cardiac effects of anthracycline-based therapy in childhood cancer survivors: a CMR study of cardiac strain and function

Clinical Evaluation of [18F]AlF-NOTA-GL01 PET/CT in patients with solid tumors: a prospective comparison with [18F]FDG and an exploratory [18F]FAPI-42 subset

Pharmacological interventions targeting cognition and related clinical outcomes in vascular dementia: a systematic review and meta-analysis of randomized controlled trials

Correction to: Predicting Aneurysm Occlusion After Flow Diversion:

Transcriptional Profiling of Growth Hormone–Secreting Pituitary Adenoma Stem‐Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications

Emerging chemical and biotechnological approaches for sustainable treatment of food industrial wastewater and resource valorization: a review

Multidisciplinary Oral Rehabilitation in Osteogenesis Imperfecta: 18‐Year‐Old Case Report

Hepatotoxicity of Avacopan: Real‐World Incidence and Confirmed Cases of Severe Drug‐Induced Liver Injury in a US National Rheumatology Registry

NCT07782723: A Comparison of the Effects of Combining ESWT With Blood Flow Restriction Therapy in Patients Diagnosed With Lateral Epicondylitis: a Randomized Controlled Trial

Study type: INTERVENTIONAL. Phase: NA.

NCT07781969: Clinical Evaluation of Discoloration Induced by Root Canal Treatment in Vital and Devital Teeth: A Prospective Study

Study type: OBSERVATIONAL. Phase: .

NCT07781618: 3D Foot Scanning and Customized 3D-Printed Foot Orthotics to Reduce Pressure on the Feet of Healthy Adults

Study type: INTERVENTIONAL. Phase: NA.

NCT07781345: A Postmarketing Study of LEQEMBI in United Kingdom (UK) Participants With Alzheimer's Disease (AD)

Study type: OBSERVATIONAL. Phase: .

NCT07780890: A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

Study type: OBSERVATIONAL. Phase: .