Pharmaceutical industry news

NIH award: Advancing population-based research on cognitive aging and dementia with minimally-invasive methods for quantifying biomarkers of neurocognitive function

Recipient: NORTHWESTERN UNIVERSITY. Award amount: 440000.

NIH award: Integrated Multiomics Diagnostics at the Point of Care for Healthy Living

Recipient: INNOTECH PRECISION MEDICINE, INC. Award amount: 365004.

NIH award: Interplay between common and rare variants associated with schizophrenia

Recipient: UNIV OF NORTH CAROLINA CHAPEL HILL. Award amount: 827625.

NIH award: Subclinical kidney and cardiovascular indicators of transplant-associated thrombotic microangiopathy (TMA)

Recipient: CINCINNATI CHILDRENS HOSP MED CTR. Award amount: 638652.

NIH award: Exploring the Molecular Link between Bioenergetics, Latency, and Neuro-cognitive Impairment during HIV-associated progressive Aging

Recipient: UNIVERSITY OF NEBRASKA MEDICAL CENTER. Award amount: 2571326.

NIH award: An ecological momentary investigation of associations between PTSD, alcohol use, and medication adherence among young adults

Recipient: OHIO STATE UNIVERSITY. Award amount: 713536.

NIH award: Advancing Actionability in Oncology: Enhanced Detection of Head and Neck Cancer Recurrence

Recipient: ILLUMIFYDX, INC.. Award amount: 396280.

NIH award: Audiom: Developing an Indoor Non-Visual Mapping System

Recipient: XR NAVIGATION INC.. Award amount: 977598.

NIH award: Optimizing ModiFlow Geometry for Enhanced Efficiency of Aerosol Drug Delivery

Recipient: ENERGYBIOCODE LLC. Award amount: 306799.

NIH award: Combating APS-associated Neutrophil Activation with Colchicine

Recipient: UNIVERSITY OF MICHIGAN AT ANN ARBOR. Award amount: 361409.

NIH award: Identifying Unmet Needs to Support Individuals Impacted by Misattributed Parentage Events (The SupportSeq Study)

Recipient: BAYLOR COLLEGE OF MEDICINE. Award amount: 440000.

NIH award: Modulating ER stress-induced lipotoxicity to ameliorate mitochondrial myopathy

Recipient: WEILL MEDICAL COLL OF CORNELL UNIV. Award amount: 396206.

NIH award: Engineering Neuroresilience: Investigating Tardigrade Neuroprotection to Identify Translatable Strategies

Recipient: UNIVERSITY OF CALIFORNIA SANTA BARBARA. Award amount: 123066.

NIH award: Development and validation of a cell separation platform technology

Recipient: HALCYON BIOMEDICAL, INC.. Award amount: 351949.

NIH award: Understanding Gastrointestinal Cancer Disparities among Native Hawaiians / Pacific Islanders

Recipient: UNIVERSITY OF HAWAII AT MANOA. Award amount: 727499.

NIH award: Core 2: Advanced Dosimetry, Modeling, Biostatistics

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 119379.

NIH award: Core 1: Biorepository, Data Acquisition

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 103569.

NIH award: Project 3: Plasma and Tissue Biomarkers in Neoadjuvant CRT for EGC

Recipient: MASSACHUSETTS GENERAL HOSPITAL. Award amount: 442675.

NIH award: UniProt: AI-Driven Scaling of Protein Knowledge for Biomedical Research

Recipient: GEORGETOWN UNIVERSITY. Award amount: 875383.

NIH award: Engineered extracellular vesicles for the delivery of mitochondria and therapeutic proteins to the BBB

Recipient: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON. Award amount: 405531.

NIH award: Neural basis of structure learning for value inference in the orbitofrontal cortex

Recipient: HARVARD UNIVERSITY. Award amount: 120582.

NIH award: A randomized trial to determine impact, cost and cost effectiveness of pharmacy-based PrEP on PrEP continuation for women at high risk of HIV

Recipient: CENTRE/SEXUAL HLTH/HIV AID RES/ZIMBABWE. Award amount: 504476.

NIH award: Measuring input-output operations of cortical neurons with large-scale neurotransmitter imaging

Recipient: ALLEN INSTITUTE. Award amount: 1068000.

Relationship between factors of mental and physical health in medical students

PersonMe: A clinical trial for Personalised Psychiatry from your Sofa

A Women-Centred Approach: Development of a Randomized Controlled Trial Evaluating the efficacy of a Human-Supported Online Intervention for Depression and the Metabolic Signature of Personalized Treatment Response

Randomized clinical trial of a novel food insecurity intervention for patients with opioid use disorder: Unexpected improvements in depression, quality of life and pain outcomes

Switching from Amisulpride to Cariprazine: Real-world outcomes in patients with predominant negative symptoms

An open-label trial to compare exposures of subcutaneous long-acting injectable use olanzapine (TV-44749) versus oral olanzapine in adults with schizophrenia (ORBIT)

Agreement and Divergence Between Clinician-Rated and Self-Report Measures of Depression Symptom Severity

Demographic Disparities in Clinical Trials of Xanomeline–Trospium for Schizophrenia: A Cross-Sectional Analysis of Data from ClinicalTrials.gov

Industry updates from the field of stem cell research and regenerative medicine in June 2025

Anti-Lung Cancer Agent Discovery and Development: A Review of Cross-Platform Correlation Across in silico, Network Pharmacology, in vitro, and in vivo Assessments.

Esketamine for Postoperative Anxiety After Major Abdominal Tumor Surgery: A Randomized Clinical Trial.

Letter to the Editor Regarding "Effects of Desflurane and Propofol General Anesthesia on Postoperative Recovery Quality in Elderly Patients Undergoing Spinal Surgery: A Randomized Non-Inferiority Trial" [Letter].

Discovering repurposable drugs for Alzheimer's disease and related dementias: target trial emulation using decentralised real-world data.

A landscape analysis of Japanese tolerability assessments in oncology drug development.

Characterizing Time Toxicity in Lung Cancer Clinical Trials: Development and Application of a Novel Time Burden Metric.

Safety and pharmacokinetics of CL-197, a potent compound with low cytotoxicity against HIV-1: a randomized, double-blind, placebo-controlled, first-in-human phase 1 clinical trial.

Long-term hormone therapy for perimenopausal and postmenopausal women.

A review of seamless phase I/II trial designs towards oncology dose optimization with examples of clinical pharmacology considerations in early drug development.

Antimicrobial Susceptibility Patterns among Urinary Bacterial Isolates: A Descriptive Analysis of Ten Consecutive Clinical Cases

CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF ATOPIC DERMATITIS SEVERITY IN CHILDREN: THE ROLE OF TOTAL IGE, EOSINOPHILIA, AND POLYSENSITIZATION

Computed tomography portal venous reconstruction assisted endoscopic ultrasound-guided selective inflow vessel devascularization for the treatment of type 1 gastroesophageal varices

Comparative in vitro Evaluation of Systemic Fungicides and Bioagents against Pigeonpea Wilt Caused by Fusarium oxysporum f. sp. udum

<b>Prevalence, Clinical Profile, and Risk Factors of Peripheral Arterial Disease in Patients on Maintenance Hemodialysis</b>

Clinical Complexities in Vulnerable Populations: A Comprehensive Review of Hemophagocytic Lymphohistiocytosis Diagnostics and the Long-Term Neurodevelopmental Sequelae of Preterm Birth

The clinical spectrum of adult patients with hypercalcaemia attending a tertiary centre in South Africa

Changing Clinical Characteristics, Diagnostic Patterns, and Outcomes of Tuberculosis in South Korea: The Korean Tuberculosis Cohort, 2019-2024

Clinical outcomes of radiation therapy as an alternative to radical surgery for early-stage rectal cancer

CYP2D6 genetic variation and clinical response to donepezil and galantamine in Alzheimer’s disease: a systematic review and meta-analysis

Inflammatory Bowel Disease in Kazakhstan: Phenotypes, Disease Activity, and Treatment Patterns from a National Registry

Real-World Treatment Patterns and Clinical Outcomes After First-Line Therapy in Patients with KRAS G12C-Mutant Advanced Non-Small-Cell Lung Cancer in the United States

Effects of 21-day vitamin D supplementation on sports performance and exercise-induced inflammation: a randomized double-blind trial

AutoGluon-based interpretable machine learning for clinical risk stratification of retinopathy of prematurity in very preterm infants

Anastomotic leak after esophagectomy for cancer in enhanced recovery protocol versus conventional care: clinical characteristics and outcomes

An open-label randomised controlled trial protocol evaluating a Siddha add-on regimen for radiotherapy induced oral mucositis in head and neck cancer patients

Short-term postoperative neurocognitive safety and recovery profiles of remimazolam tosilate combined with flumazenil vs. propofol in cirrhotic patients undergoing endoscopic variceal treatment: a randomized controlled trial

Synergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and development of an explainable web-based clinical calculator

Spatial niches of the colorectal cancer microbiome: differences, interrelationships, and clinical implications of fecal, mucosal, and intratumoral microbiota